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Perospirone
go.drugbank.com/drugs/DB08922InvestigationalIt is also shown to be less associated with extrapyramidal symptoms as a side effect compared to [DB00502]. … Classified as a neuroleptic agent, perospirone is shown to be effective against positive, negative and general symptoms in patients with schizophrenia [A19676].
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: SM-9018, cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximideBI-K0376
go.drugbank.com/drugs/DB05858ExperimentalBI-K0376 is investigated for use/treatment in acne. BI-K0376 is a solid. It is under investigation by Pfizer and has gone through phase I of the clinical trails.
Technetium Tc-99m ciprofloxacin
go.drugbank.com/drugs/DB05488Experimental99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis … INFECTON combines the widely used antibiotic, ciprofloxacin, with Technetium ((99m)Tc), the most commonly used radioisotope in nuclear medical imaging There is currently controversy around the drug's ability
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingOlokizumab
go.drugbank.com/drugs/DB13127Investigational[A241185, A241175] Olokizumab is a humanized anti-IL-6 IgG4κ antibody that directly blocks gp130 binding at IL-6 Site 3.[A241045] … Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system.
Meclofenamic acid
go.drugbank.com/drugs/DB00939ApprovedInvestigationalVet approvedA non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Categories: Non COX-2 selective NSAIDSSynonyms: N-(2,6-dichloro-m-tolyl)anthranilic acid, N-(2,6-dichloro-3-methylphenyl)anthranilic acidTenofovir
go.drugbank.com/drugs/DB14126Investigational[A37693] In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. … Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate.
Synonyms: (R)-PMPACategories: P-glycoprotein substrates, Heterocyclic Compounds, 2-RingLevonordefrin
go.drugbank.com/drugs/DB06707ApprovedInvestigationalLevonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Mixtures: Scandonest 2% L, Scandonest LSynonyms: L-Nordefrin, L-alpha-methylnoradrenalineDydrogesterone
go.drugbank.com/drugs/DB00378ApprovedInvestigationalWithdrawnA synthetic progestational hormone with no androgenic or estrogenic properties.
Mixtures: FEMOSTON CONTI 1/5 TABLET, FEMOSTON CONTI 1/5Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHydrocortamate
go.drugbank.com/drugs/DB00769ApprovedHydrocortamate is a synthetic glucocorticoid used for its anti-inflammatory or immunosuppressive properties to treat inflammation due to corticosteroid-responsive dermatoses. … Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersPropantheline
go.drugbank.com/drugs/DB00782ApprovedA muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Categories: Heterocyclic Compounds, 3-Ring