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Chlorcyclizine
go.drugbank.com/drugs/DB08936ApprovedChlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. … Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can be used as an antiemetic.
Clorgiline
go.drugbank.com/drugs/DB04017ExperimentalAn antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeLauric acid
go.drugbank.com/drugs/DB03017ApprovedLauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses. … Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression.
Atractylodes japonica root oil
go.drugbank.com/drugs/DB11270ApprovedWithdrawnAtractylodes japonica root oil is obtained from the roots of Atractylodes japonica, which is a herb native to eastern Asia. … Atractylodes japonica is reported to have anti-inflammatory and antinociceptive effects [A27223].
Besifloxacin
go.drugbank.com/drugs/DB06771ApprovedBesifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
TA-NIC
go.drugbank.com/drugs/DB05445InvestigationalIt is designed to raise anti-nicotine antibodies which bind to nicotine molecules in the patient's blood stream, reducing the rate and quantity of nicotine entry into the brain, to reduce the addictive … TA-NIC is a novel and proprietary vaccine in development as an aid to quitting smoking in motivated patients.
Synonyms: TA-NICPerhexiline
go.drugbank.com/drugs/DB01074ApprovedPerhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Glisoxepide
go.drugbank.com/drugs/DB01289InvestigationalThese results are consistent with the transport of glisoxepide via the transport system for the unconjugated bile acid cholate. [A31819,A31820] … Glisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes.
2-Methoxyestradiol
go.drugbank.com/drugs/DB02342Investigational2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). … It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.
m-Chlorophenylpiperazine
go.drugbank.com/drugs/DB12110Investigationalm-Chlorophenylpiperazine has been used in trials studying the treatment of Alcoholism.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome