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3',5'-cyclic-nucleotide phosphodiesterase
go.drugbank.com/bio_entities/BE0010168TargetRabbitPolypeptides: 3',5'-cyclic-nucleotide phosphodiesteraseFunction: 3',5'-cyclic-AMP phosphodiesterase activity5'-AMP-activated protein kinase
go.drugbank.com/bio_entities/BE0011011TargetRatCatalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:14511394). In response to reduction of intracellular ATP levels, AMPK activa...
Polypeptides: 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit beta-2Synonyms: 5'-AMP-activated protein kinase 40 kDa subunitPyrroline-5-carboxylate reductase 2
go.drugbank.com/bio_entities/BE0000728TargetHumansOxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H (PubMed:23024808, PubMed:2722838, PubMed:6894153
Polypeptides: Pyrroline-5-carboxylate reductase 2Function: pyrroline-5-carboxylate reductase activityInosine-5'-monophosphate dehydrogenase 1
go.drugbank.com/bio_entities/BE0000761TargetEnzymeHumansCatalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays
Polypeptides: Inosine-5'-monophosphate dehydrogenase 1Glutamate receptor ionotropic, kainate 5
go.drugbank.com/bio_entities/BE0000828TargetHumansIonotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Cannot form functional channels on its own and produces channel activity only in...
Polypeptides: Glutamate receptor ionotropic, kainate 5DNA (cytosine-5)-methyltransferase 1
go.drugbank.com/bio_entities/BE0000892TargetHumansDNA methyltransferase that methylates CpG residues (PubMed:17200670, PubMed:18754681, PubMed:21745816, PubMed:26070743). Preferentially methylates hemimethylated DNA (PubMed:21745816, PubMed:26070743). Associates with DNA replication sit...
Polypeptides: DNA (cytosine-5)-methyltransferase 1Function: DNA (cytosine-5-)-methyltransferase activityN-(5'-phosphoribosyl)anthranilate isomerase
go.drugbank.com/bio_entities/BE0001549TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Polypeptides: N-(5'-phosphoribosyl)anthranilate isomeraseRibose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001628TargetShigella flexneriCatalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Polypeptides: Ribose-5-phosphate isomerase AFunction: ribose-5-phosphate isomerase activityPyridoxine/pyridoxamine 5'-phosphate oxidase
go.drugbank.com/bio_entities/BE0002066TargetEscherichia coli (strain K12)Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
Polypeptides: Pyridoxine/pyridoxamine 5'-phosphate oxidaseSynonyms: Pyridoxal 5'-phosphate synthaseGlutathione S-transferase Mu 5
go.drugbank.com/bio_entities/BE0002285TargetEnzymeHumansConjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles
Polypeptides: Glutathione S-transferase Mu 5Synonyms: GSTM5-5, GST class-mu 5