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Displaying results 3651 - 3660 of 10000 in total
  1. Drug

    Proscillaridin

    go.drugbank.com/drugs/DB13307
    Experimental

    Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). … Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations [A27193

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    MBO7133

    go.drugbank.com/drugs/DB04999
    Experimental

    However, araC is only slowly converted to araCTP in the liver or in primary liver tumors due to low levels of an enzyme in the liver that is required for the conversion of araC to araCMP, the first step … in the activation pathway of the drug.

  3. Drug

    ADH-1

    go.drugbank.com/drugs/DB05485
    Investigational

    At the end of 2006, the Company also completed patient enrollment in our single-agent Phase Ib/II and Phase II trials of ADH-1. … Poorly differentiated, highly invasive carcinomas are characterized by over-expression of N-cadherin (as opposed to E-cadherin).

    Synonyms: l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide
  4. Drug

    Boron

    go.drugbank.com/drugs/DB11203
    ApprovedInvestigational

    Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. … additive in glass fibers of boron-containing fiberglass for insulation and structural materials.

    Mixtures: Ribotin-E
  5. Drug

    3,3'-diindolylmethane

    go.drugbank.com/drugs/DB11875
    Investigational

    Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Thioredoxin

    go.drugbank.com/drugs/DB11298
    Approved

    It plays an essential role as an antioxidant in neutralizing food allergens and redox signalling. Allergens containing disulfide bonds are inactivated when reduced by thioredoxin. … Thioredoxin is a small dithiol protein and specific reductant for major allergenic proteins present in foods from animal and plant products.

  7. Drug

    Terfenadine

    go.drugbank.com/drugs/DB00342
    ApprovedWithdrawn

    In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

  8. Drug

    Propylhexedrine

    go.drugbank.com/drugs/DB06714
    Approved

    Propylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. It is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies.

  9. Drug

    Ferrous asparto glycinate

    go.drugbank.com/drugs/DB11169
    Approved

    Ferrous asparto glycinate is an iron-amino acid chelate. It is available as a dietary supplement used in the treatment of iron deficiency and iron deficiency anemia.

  10. Drug

    Ularitide

    go.drugbank.com/drugs/DB05034
    Investigational

    Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the systemic blood circulation. … Ularitide is currently in Phase 2 development as a potential treatment for patients with acute decompensated heart failure (ADHF).