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PBI-1402
go.drugbank.com/drugs/DB05480ExperimentalSince it stimulates immune activity, it has been considered as a candidate for cancer treatment as well as anemia. … PBI-1402 appears to work on the PMN pathway, but its specific binding properties are not known. PBI-1402 has a dual therapeutic action; as a chemoprotectant and hematopoietic progenitor stimulator.
Rimiducid
go.drugbank.com/drugs/DB04974InvestigationalRimiducid is a lipid-permeable tacrolimus analogue and a protein dimerizer. … [A187496,L9521] The combination use of rimiducid with immunotherapies for enhanced therapeutic effectiveness is currently under investigation.
GR270773
go.drugbank.com/drugs/DB06427InvestigationalNCT00089986 (completed with results, treatment of suspected or confirmed gram-negative severe sepsis in adults, comparing GR270773 with a placebo). … GR270773, was investigated in two clinical trials for its potential to treat sepsis: NCT00158769 (completed, comparing the effects of infusion between healthy adults and those with damaged livers) and
Nitrite
go.drugbank.com/drugs/DB12529ApprovedWithdrawnNitrite is under investigation for the treatment of Heart Failure.
Tozorakimab
go.drugbank.com/drugs/DB16473InvestigationalCOPD patients with a history of exacerbations), and NCT06040086 (recruiting; symptomatic COPD with a history of exacerbations). … Tozorakimab (MEDI3506), developed by AstraZeneca, was investigated in multiple clinical trials to evaluate its safety, tolerability, efficacy, and pharmacokinetics across various conditions.
Categories: Experimental Unapproved Treatments for COVID-19Etesevimab
go.drugbank.com/drugs/DB15897Investigational[L16651,L16661] Under the EUA granted in February 2021, etesevimab is used in combination with [bamlanivimab] to treat mild to moderate COVID-19 in adults and pediatric patients who are at high risk for … Etesevimab (LY-CoV016, also known as JS016) is a fully human and recombinant monoclonal antibody that targets the SARS-CoV-2 surface spike protein receptor binding domain.
Categories: Experimental Unapproved Treatments for COVID-19Potassium carbonate
go.drugbank.com/drugs/DB13977ApprovedPotassium carbonate (K2CO3) is a white salt, soluble in water (insoluble in ethanol) which forms a strongly alkaline solution. … It presents a large capacity to absorb moisture.
Mixtures: Buffered Vitamin C Powder With Ca Mg and K, ZOLFO E POTASSIO CARBONATO NEW.FA.DEM.Nitrendipine
go.drugbank.com/drugs/DB01054ApprovedWithdrawnNitrendipine is a calcium channel blocker with marked vasodilator action. … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Products: NITRENDIPIN AL 10, NITRENDIPIN AL 20GTI-2501
go.drugbank.com/drugs/DB05406ExperimentalThe drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer. … GTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial.
Meclocycline
go.drugbank.com/drugs/DB13092InvestigationalMeclocycline is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment of Oral Mucositis) [L797].
Categories: Anti-Acne Preparations for Topical Use, Antiinfectives for Treatment of Acne