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Displaying results 361 - 370 of 10000 in total
  1. Drug

    Sodium citrate

    go.drugbank.com/drugs/DB09154
    ApprovedInvestigational

    Sodium citrate is the sodium salt of citric acid. … From the medical point of view, it is used as alkalinizing agent. It works by neutralizing excess acid in the blood and urine. It has been indicated for the treatment of metabolic acidosis.

    Mixtures: N-ORS Oral Rehydration Salts (Orange Flavour), REGIOCIT SOLUTION FOR HAEMOFILTRATIONCategories: Compounds used in a research, industrial, or household setting, Salt Solutions
  2. Drug

    Botulinum toxin type A

    go.drugbank.com/drugs/DB00083
    ApprovedInvestigational

    In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. … [A231819,L32569] A popular use for Botox is the treatment of facial wrinkles and lines, however, there are many uses for the botulinum toxin A in the treatment of dystonia, incontinence, migraine, blepharospasm

    Products: BOTOX (BOTULINUM TOXIN TYPE A) IM INJECTION, XEOMIN powder for solution for injection 100 LD50 units
  3. Drug

    Dexpanthenol

    go.drugbank.com/drugs/DB09357
    ApprovedInvestigational

    Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism … Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products, such as ointments and lotions for treatment of dermatological conditions to relieve itching or

    Mixtures: Venobene - Salbe, TAMIPOOL FOR INJECTIONCategories: Preparations for Treatment of Wounds and Ulcers
  4. Drug

    Urokinase

    go.drugbank.com/drugs/DB00013
    ApprovedInvestigationalWithdrawn

    Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. … [A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138]

    Products: Kinlytic (urokinase for Injection), UROKINASE-GREEN CROSS INJ. 60,000 iu/vial
  5. Drug

    Pegaspargase

    go.drugbank.com/drugs/DB00059
    ApprovedInvestigational

    [A255912,A255917] In February 1994, pegaspargase was approved by the FDA for the treatment of ALL in patients with hypersensitivity to native forms of L-asparaginase.[A255927] … [A103,A255912,L44667] Pegaspargase has the same mechanism of action as [L-asparaginase] derived from _Escherichia coli_, a previously developed enzyme used for the treatment of acute lymphoblastic

    Categories: Compounds used in a research, industrial, or household settingProducts: ONCASPAR POWDER FOR SOLUTION FOR INJECTION/INFUSION 750 U/ML, Oncaspar 750 U/ml powder for solution for injection/infusion
  6. Drug

    Dulaglutide

    go.drugbank.com/drugs/DB09045
    ApprovedInvestigational

    [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular … therapy to diet and exercise in the management of 2 diabetes (T2DM).

    Categories: Drugs Used in DiabetesProducts: Trulicity 1.5mg solution for injection in pre-filled pen, Trulicity 0.75mg solution for injection in pre-filled pen
  7. Drug

    Simoctocog alfa

    go.drugbank.com/drugs/DB09108
    Approved

    As patients with haemophilia A are predisposed to episodes of recurrent bleeding [L1115], simoctocog alfa can be administered for the treatment or prevention of bleeding such as prior to surgical procedures … Full human post-translational modifications via elimination of potentially immunogenic glycosylation patterns found in non-human cell lines led to decreased immunogenicity and longer half-life [A31525]

    Products: NUWIQ 500 UI, NUWIQ 2000 UI
  8. Drug

    Potassium hydroxide

    go.drugbank.com/drugs/DB11153
    Approved

    Recently, it has been studied for efficacy and tolerability in the treatment of warts. … It was determined that topical KOH solution was found to be a safe and effective treatment of plane warts [L1941].

    Mixtures: Nutriflex Peri Solution for Infusion, Vamin NCategories: Compounds used in a research, industrial, or household setting, Potassium Salt
  9. Drug

    Triptorelin

    go.drugbank.com/drugs/DB06825
    ApprovedInvestigationalVet approved

    Serum testosterone concentrations may fall to levels typically observed in surgically castrated men. … After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis.

    Products: Triptofem 0,1 mg/ml Injektionslösung in einer Fertigspritze, Decapeptyl Depot - Retardmikrokapseln und Suspensionsmittel in Einmalspritzen
  10. Drug

    Famotidine

    go.drugbank.com/drugs/DB00927
    ApprovedInvestigational

    [L11166] While oral formulations of famotidine are more commonly used, the intravenous solution of the drug is available for use in hospital settings.[L11142] … It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children.

    Synonyms: N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide, 3-(((2-((Aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-N-(aminosulfonyl)propanimidamideInternational brands: Sedanium-R