Search

Displaying results 361 - 370 of 1804 in total
  1. Target

    Motilin receptor

    go.drugbank.com/bio_entities/BE0003521
    TargetHumans

    Receptor for motilin

    Polypeptides: Motilin receptorSynonyms: G protein-coupled receptor 38
  2. Target

    Transferrin receptor

    go.drugbank.com/bio_entities/BE0004850
    TransporterTargetHumans

    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738, PubMed:41772062). … The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.

    Polypeptides: Transferrin receptor protein 1, Transferrin receptor protein 2Synonyms: Transferrin receptor 1
  3. Target

    Dopamine receptor

    go.drugbank.com/bio_entities/BE0009376
    TargetHumans

    Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity). … Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:39094559)

    Polypeptides: Dopamine receptor D1, Dopamine receptor D2Synonyms: Dopamine D1 receptor, Dopamine D2 receptor
  4. Drug

    Foreskin fibroblast (neonatal)

    go.drugbank.com/drugs/DB10770
    Approved

    Dermagraft has been combined with [DB10772] to create a drug beneficial to patients with open burn wounds [L2427].

  5. Drug

    Titanium dioxide

    go.drugbank.com/drugs/DB09536
    Approved

    Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmen...

    Mixtures: Vita Water Drop Cc, Skinfood Vita Water Drop CcProducts: Missha M Vita Bb Spf20, Nutritious Vita-mineral Makeup SPF 10
  6. Drug

    Vitamin D

    go.drugbank.com/drugs/DB11094
    ApprovedInvestigationalNutraceuticalVet approved

    Vitamin D ultimately comprises a group of lipid-soluble secosteroids responsible for a variety of biological effects, some of which include increasing the intestinal absorption of calcium, magnesium, and phosphate. With reference to huma...

    Mixtures: Liqui Vita, Vita Plex Tab
  7. Target

    Androgen receptor

    go.drugbank.com/bio_entities/BE0000132
    TargetHumans

    activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor

    Polypeptides: Androgen receptorSynonyms: Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
  8. Target

    Calcitonin receptor

    go.drugbank.com/bio_entities/BE0000431
    TargetHumans

    Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. … CALCR interacts with receptor-activity-modifying proteins RAMP1, 2 and 3 to form receptor complexes AMYR1, 2 and 3, respectively (PubMed:35324283, PubMed:38603770).

    Polypeptides: Calcitonin receptorFunction: amylin receptor activity
  9. Target

    Mineralocorticoid receptor

    go.drugbank.com/bio_entities/BE0000668
    TargetHumans

    Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol.

    Polypeptides: Mineralocorticoid receptorSynonyms: Nuclear receptor subfamily 3 group C member 2
  10. Target

    Oxytocin receptor

    go.drugbank.com/bio_entities/BE0000844
    TargetHumans

    G protein-coupled receptor for oxytocin (OXT), a neuropeptide hormone released by the posterior pituitary gland that plays a key role in social behavior and other biological processes, such as milk ejection … Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as phospholipase C (PubMed

    Polypeptides: Oxytocin receptorFunction: oxytocin receptor activity