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Gadobutrol
go.drugbank.com/drugs/DB06703ApprovedInvestigationalGadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. … Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser injection volume.
Categories: Compounds used in a research, industrial, or household settingProducts: Gadograf 1,0 mmol/ml Injektionslösung in Fertigspritzen, Gadovist 1,0 mmol/ml Injektionslösung in Fertigspritzen/PatronenFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin.
Synonyms: N-phenethyl-4-(N-propionylanilino)piperidine, N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamideMixtures: Innovar InjTobramycin
go.drugbank.com/drugs/DB00684ApprovedInvestigational[L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics … [A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a variety of forms for administration by inhalation, injection, and external application to
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Tobramycin in Sodium Chloride, Nebcin Inj 80mgMexiletine
go.drugbank.com/drugs/DB00379ApprovedInvestigationalIt may have some anticonvulsant properties.
Synonyms: (±)-1-(2,6-dimethylphenoxy)propan-2-amineCategories: Antiarrhythmics, Class I, Antiarrhythmics, Class IbHyaluronidase
go.drugbank.com/drugs/DB14740ApprovedInvestigational[L13338] The action of hyaluronidase was first described in 1936, and named in 1939. … [A199026] Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue.
Products: Wydase Inj 150unit/ml, HYLASE® DESSAU 150 IUPancuronium
go.drugbank.com/drugs/DB01337ApprovedA bis-quaternary steroid that is a competitive nicotinic antagonist. … As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.
Products: Pavulon Inj 2mg/ml, Pavulon Inj 1mg/mlGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigationalGanirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999.
Products: Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze, Ganirelix Theramex 0,25 mg/0,5 ml Injektionslösung in einer FertigspritzeZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalIt is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States. … This drug is a liquid. This compound belongs to the thioxanthenes.
Products: CLOPIXOL-ACUPHASE INJ 50MG/ML (1ML), Clopixol Depot - Liq Im 200mg/mlSodium ferric gluconate complex
go.drugbank.com/drugs/DB09517ApprovedIt is composed of iron (III) oxide hydrate directly bonded to sucrose with a chelating gluconate function in a molar ratio of two iron molecules to one gluconate. … It is used in adult and in pediatric patients over the age of 6 years with chronic kidney disease (CKD) receiving hemodialysis and receiving supplemental epoetin therapy.
Products: Sodium Ferric Gluconate Complex in SucroseSomatostatin
go.drugbank.com/drugs/DB09099ApprovedInvestigationalWithdrawn[DB00104] is a long-acting analogue of somatostatin that inhibits the release of a number of hormones, and is clinically used to relieve symptoms of uncommon gastroenteropancreatic endocrine tumours, as … It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating
Mixtures: Stilamin - Pws Liq IVProducts: SOMATOSTATIN EUMEDICA 3 MG IV INF. ICIN LIYOFILIZE TOZ ICEREN FLAKON, Stilamin - Pws IV 3mg/amp