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Displaying results 361 - 370 of 8010 in total
  1. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.

    Products: VELETRI POWDER FOR SOLUTION FOR INFUSION 0.5MG/VIAL, VELETRI POWDER FOR SOLUTION FOR INFUSION 1.5MG/VIAL
  2. Drug

    Deferoxamine

    go.drugbank.com/drugs/DB00746
    ApprovedInvestigational

    Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.

    Categories: Compounds used in a research, industrial, or household settingProducts: Desferal 500mg Powder for Solution for Injection, Deferoxamine Mesylate for Injection
  3. Drug

    Calcium threonate

    go.drugbank.com/drugs/DB11168
    ApprovedWithdrawn

    Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement [A27266]. … The most common form is calcium L-threonate, or (2R,3S)-2,3,4-trihydroxy butyric acid calcium [A27266].

    Synonyms: Threonine, calcium salt
  4. Drug

    Fibrinogen human

    go.drugbank.com/drugs/DB09222
    ApprovedInvestigational

    It is a soluble plasma glycoprotein with a molecular weight of about 340 kDa and is a physiological substrate for three enzymes: plasmin, factor XIIIa, and thrombin. … It works by replacing a specific protein in the blood, fibrinogen (factor I), that helps with blood clotting.

    Mixtures: ARTISS SOLUTIONS FOR SEALANT, DEEP FROZEN, Artiss Solutions for Sealant, Deep FrozenProducts: HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL, Fibryga 1g Powder and Solvent for Solution for Injection or Infusion
  5. Drug

    Miconazole

    go.drugbank.com/drugs/DB01110
    ApprovedInvestigationalVet approved

    [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January 8, 1974, for sale by INSIGHT Pharmaceuticals as a topical cream. … Despite having been in clinical use for an extended period, resistance to miconazole among susceptible organisms is relatively low.[A203636]

    Mixtures: Up and Up Miconazole 1, Up and Up Miconazole 1Categories: Antifungals for Topical Use, Antifungals for Dermatological Use
  6. Drug

    Cabazitaxel

    go.drugbank.com/drugs/DB06772
    ApprovedInvestigational

    Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. … [A7056] Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel].

    Products: JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION, JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION)
  7. Drug

    Benzoyl peroxide

    go.drugbank.com/drugs/DB09096
    ApprovedInvestigational

    Benzoyl peroxide is a commonly used drug in topical treatments for acne. … [L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with [erythromycin],[L33264] [clindamycin],[L33269] or [adapalene].

    Mixtures: Target Up and Up 3 Step Acne System, Target Up and Up 3 Step Acne SystemCategories: Anti-Acne Preparations for Topical Use
  8. Drug

    Rasburicase

    go.drugbank.com/drugs/DB00049
    ApprovedInvestigational

    The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_. … Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified <i>Saccharomyces cerevisiae</i> strain.

    Categories: Detoxifying Agents for Antineoplastic TreatmentProducts: FASTURTEC POWDER FOR SOLUTION FOR INFUSION 1.5 mg/vial
  9. Drug

    Ferrous gluconate

    go.drugbank.com/drugs/DB14488
    ApprovedInvestigational

    Mixtures: Multi-force for Women Tab, Multi-force for Adults TabSynonyms: D-gluconic acid, iron(2+) salt (2:1)
  10. Drug

    Tasonermin

    go.drugbank.com/drugs/DB11626
    Approved

    It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft tissue sarcoma … Tasonermin is recombinant soluble form tumor necrosis factor &alpha; produced via _Escherichia coli_ cell culture.

    Synonyms: Tumor necrosis factor, soluble form, nonglycosylated