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CoronaVac
go.drugbank.com/drugs/DB15806InvestigationalAs of August 2020, the vaccine is being tested in numerous human clinical trials assessing its safety and immunogenicity. … In preclinical trials, PiCoVacc induced SARS-CoV-2-specific neutralizing antibodies in rats, mice, and the rhesus macaque.
Aspergillus fumigatus
go.drugbank.com/drugs/DB10425ApprovedAspergillus fumigatus extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureCochliobolus sativus
go.drugbank.com/drugs/DB10433ApprovedCochliobolus sativus extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureMycobacterium w. Vaccine
go.drugbank.com/drugs/DB15798InvestigationalIt has protective efficacy against M. tuberculosis and M. leprae. As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … As an immunotherapy, M.w is used against leprosy; the compound also shares antigens with M. tuberculosis.
LCP-AtorFen
go.drugbank.com/drugs/DB05769Investigationaltreatment of high cholesterol levels, addressing three primary cardiovascular risk factors: low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglycerides (TG
Gepirone
go.drugbank.com/drugs/DB12184ApprovedAlthough earlier clinical trials showed promising results for gepirone, its formulation as an immediate-release tablet necessitates frequent administration due to the short half-lives. … Gepirone, an azapirone, is a pharmacologic analog of [buspirone] that acts selectively on the pre- and post-synaptic 5HT<sub>1A</sub> receptors.
Metyrosine
go.drugbank.com/drugs/DB00765ApprovedInvestigationalIt is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed) … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines.
Metergoline
go.drugbank.com/drugs/DB13520Approved[A27181] Its use has been studied in various clinical settings such as a treatment for seasonal affective disorder, prolactin hormone regulation due to its inhibitory effect on prolactin release,[A27182 … ] premenstrual dysphoric disorder in women and antianxiety treatment.
Dimethylthiambutene
go.drugbank.com/drugs/DB01444ExperimentalIllicitDimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug. … It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
Synonyms: N,N,1-trimethyl-3,3-di-2-thienylallylamine, N,N-dimethyl-4,4-di(2-thienyl)-3-buten-2-amine