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Displaying results 3721 - 3730 of 6951 in total

Drug
Practolol
go.drugbank.com/drugs/DB01297
Approved
A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Categories: Adrenergic beta-1 Receptor Antagonists
Drug
Entacapone
go.drugbank.com/drugs/DB00494
ApprovedInvestigational
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols.
Drug
Sodium tartrate
go.drugbank.com/drugs/DB13707
ApprovedWithdrawn
Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) ...
Categories: Drugs for Constipation
Drug
J147
go.drugbank.com/drugs/DB13957
Experimental
[A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
Drug
Mefloquine
go.drugbank.com/drugs/DB00358
Approved
[L30623] Mefloquine, commonly known as Lariam, is an antimalarial drug used for the prevention and treatment of malaria caused by infection with Plasmodium vivax and Plasmodium falciparum. … Individuals at the highest risk for malaria are those in disease naïve populations, children under age 5, refugees in Central and Eastern Africa, nonimmune civilian and military travelers, pregnant women
Drug
GC-376 free acid
go.drugbank.com/drugs/DB15796
Experimental
These results suggest that GC-376, and its metabolites may have therapeutic potential for Covid-19. … The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov infections[A219036,A219056].
Categories: Experimental Unapproved Treatments for COVID-19
Drug
Ozanimod
go.drugbank.com/drugs/DB12612
ApprovedInvestigational
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. … [L41524] In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.
Categories: Sphingosine 1-phosphate Receptor Modulator, Sphingosine 1 Phosphate Receptor Modulators
Drug
Cortisone
go.drugbank.com/drugs/DB14681
Investigational
It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive.
Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, Plain
Drug
Estradiol cypionate
go.drugbank.com/drugs/DB13954
ApprovedVet approved
Estradiol cypionate is commercially available as Depo-Estradiol, an intramuscular depot injection used for the treatment of moderate to severe vasomotor symptoms associated with menopause and for the treatment … As a pro-drug of estradiol, estradiol cypionate therefore has the same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and ERβ subtypes, which are located
Categories: Hormonal Contraceptives for Systemic Use
Drug
Odronextamab
go.drugbank.com/drugs/DB16684
ApprovedInvestigational
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma … [A254192] Odronextamab received its first approval in the European Union on August 26, 2024, for the treatment of relapsed or refractory (R/R) follicular lymphoma (FL) or R/R diffuse large B-cell lymphoma