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Merbromin
go.drugbank.com/drugs/DB13392InvestigationalIt is an organomercuric disodium salt compound and a fluorescein that is available in many countries, except Switzerland, France, Germany, and the United States where the drug was withdrawn from market
Methacholine
go.drugbank.com/drugs/DB06709Approved[L31763] In patients with AHR, a lower dose of methacholine is required to induce bronchoconstriction, which forms the basis for the methacholine challenge test to diagnose AHR. … [A229648, L31763] Methacholine was granted FDA approval on October 31, 1986, and is marketed under the trademark PROVOCHOLINE® by Methapharm Inc.[L31763]
Sofpironium
go.drugbank.com/drugs/DB19325Approved[L51108,L51109] Sofpironium bromide (Sofdra) was approved by the FDA in June 2024 for the topical treatment of primary axillary hyperhidrosis. … [L51109] Soft drugs are designed to reduce systemic toxicity while enhancing local efficacy by employing retrometabolic drug design, in which a molecule contains a metabolically sensitive moiety that promotes
Gadofosveset trisodium
go.drugbank.com/drugs/DB06705ApprovedThe agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood vessels.
Categories: Compounds used in a research, industrial, or household settingAprocitentan
go.drugbank.com/drugs/DB15059ApprovedInvestigational[A263386,L50261] Aprocitentan was approved by the FDA in March 2024 for the treatment of hypertension in patients inadequately controlled with standard therapy. … Endothelin receptor antagonism provides a novel therapeutic pathway for the management of patients with resistant hypertension.
Axatilimab
go.drugbank.com/drugs/DB16388ApprovedInvestigational[A264309] Axatilimab was approved by the FDA in August 2024 for the third-line treatment of cGVHD. … [L51194] The mainstay of cGVHD treatment are systemic corticosteroids, but they are ineffective in 30-50% of cases.
Picric acid
go.drugbank.com/drugs/DB03651ApprovedUsed as antiseptic, astringent, and stimulant for epitheliazation.
Categories: Compounds used in a research, industrial, or household settingFerrous bisglycinate
go.drugbank.com/drugs/DB11210ApprovedIt is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.
MPT0B640
go.drugbank.com/drugs/DB16512InvestigationalMPT0B640 was under investigation in clinical trials NCT04526717 for COVID-19 infection and NCT04294875 for locally advanced or metastatic solid malignancies.
Categories: Experimental Unapproved Treatments for COVID-19