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Telavancin
go.drugbank.com/drugs/DB06402ApprovedInvestigationalMRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseRolitetracycline
go.drugbank.com/drugs/DB01301ApprovedWithdrawnA pyrrolidinylmethyl tetracycline.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseToloxatone
go.drugbank.com/drugs/DB09245ExperimentalToloxatone is an antidepressant agent, the first ever use of which was in France, 1984. It acts as a selective and reversible inhibitor of monoamine oxidase-A (MOA) [L1388].
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesAstemizole
go.drugbank.com/drugs/DB00637ApprovedWithdrawnAstemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especi...
Synonyms: 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole, 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazoleCategories: Antihistamines for Systemic Use, P-glycoprotein inhibitorsCarbazochrome
go.drugbank.com/drugs/DB09012ApprovedWithdrawnIn the future this may prevent excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on effectiveness and severity of side effects remains inconclusive. … It is an oxidation product of adrenaline which enhances the microcirculatory tone [A19747].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsInternational brands: Ge DanCerliponase alfa
go.drugbank.com/drugs/DB13173ApprovedInvestigational[L51339] It was also approved by the EMA on May 30, 2017 [L51324] and by Health Canada on December 19, 2018. … [L51319] On April 27, 2017, cerliponase alfa was first approved by the FDA as the first treatment for neuronal ceroid lipofuscinosis type 2 (CLN2), also known as TPP1 deficiency.
Navafenterol
go.drugbank.com/drugs/DB19195InvestigationalNavafenterol is under investigation in clinical trial NCT02971293 (Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871).
Isoconazole
go.drugbank.com/drugs/DB08943ApprovedIsoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Categories: Antifungals for Topical Use, Antifungals for Dermatological Use