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VPM1002
go.drugbank.com/drugs/DB15801InvestigationalThe bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. … By reducing urease C, phagosome acidification can occur, promoting phagolysosome fusion while also providing the optimal low pH for listeriolysin O stability.
Mirfentanil
go.drugbank.com/drugs/DB09175ExperimentalAt high doses, it exhibits analgesic activity which is not fully reversed by opioid antagonists, suggesting that the drug has both opioid and non-opioid mechanisms of action.
Diazepinomicin
go.drugbank.com/drugs/DB12420InvestigationalDiscovered using Thallion’s DECIPHER technology, diazepinomicin has completed preclinical studies conducted by the National Cancer Institute and Thallion to establish safety and efficacy in animal and
Desmoteplase
go.drugbank.com/drugs/DB04925InvestigationalPlasmin acts by breaking down fibrin blood clots. When a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting.
D-Tryptophan
go.drugbank.com/drugs/DB03225ExperimentalIt is an essential amino acid as defined by its growth effects on rats.
Dalfampridine
go.drugbank.com/drugs/DB06637ApprovedInvestigationalDalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Trolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedTrolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain ass...
Dihydroergocornine
go.drugbank.com/drugs/DB11273ApprovedDihydroergocornine is one of the dihydrogenated ergot compounds that present very large hypotensive effects. It is an artificial derivative of the crude extract of ergot and later purified, ergocornine. The formation of dihydroergocornin...
Suprofen
go.drugbank.com/drugs/DB00870ApprovedWithdrawnAn ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Oxprenolol
go.drugbank.com/drugs/DB01580ApprovedWithdrawnA beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.