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Safrazine
go.drugbank.com/drugs/DB09253ApprovedWithdrawnSafrazine is a member of the hydrazine family with non-selective and irreversible inhibitor effects against monoamine oxidases. In 1960, it was used as an antidepressant but it is now discontinued.
Fluorodopa (18F)
go.drugbank.com/drugs/DB13848ApprovedInvestigationalFluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes. … [L12849] Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.[L12849]
Synonyms: L-6-(18F)Fluoro-DOPA, 6-Fluoro-(18F)-L-3,4-DihydroxyphenylalanineSulforaphane
go.drugbank.com/drugs/DB12422InvestigationalIt is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Categories: Compounds used in a research, industrial, or household settingXL999
go.drugbank.com/drugs/DB05014InvestigationalXL999 induces a cell-cycle block by a mechanism distinct from those previously identified and exhibits broad antitumor activity in xenograft models. … XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation and indirectly through inhibition of the host angiogenic response.
Zongertinib
go.drugbank.com/drugs/DB18762ApprovedInvestigational[L53873,A274363] On August 8, 2025, the US FDA granted accelerated approval to zongertinib for the treatment of advanced forms of non-small cell lung cancer (NSCLC) with HER2 tyrosine kinase domain … Zongertinib is a selective, irreversible tyrosine kinase inhibitor that targets human epidermal growth factor receptor 2 (HER2).
Methylselenocysteine
go.drugbank.com/drugs/DB12697InvestigationalMethylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease.
Synonyms: SE-METHYL-SELENO-L-CYSTEINECategories: Compounds used in a research, industrial, or household settingPsychiatric anxiety
go.drugbank.com/conditions/DBCOND0099705Drugs: Acetylsalicylic acid · Amoxapine · Buspirone · Chlordiazepoxide · Clobazam · Clotiazepam +27 moreElacytarabine
go.drugbank.com/drugs/DB05494InvestigationalElacytarabine is a fatty acid derivative of [cytarabine], an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia. … Elacytarabine is designed to overcome this limitation and has shown considerable uptake in solid tumour cells.
Antazoline
go.drugbank.com/drugs/DB08799ApprovedAntazoline is a 1st generation antihistamine with anticholinergic activity. It is used to relieve nasal congestion.
Synonyms: 2-(N-Phenyl-N-benzylaminomethyl)imidazoline, 4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamineInternational brands: Vasocon-aXamoterol
go.drugbank.com/drugs/DB13781ApprovedXamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. … It modulates the sympathetic control of the heart but has no agonist action on β2-adrenoceptors.