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Displaying results 371 - 380 of 10000 in total
  1. Drug

    Butylscopolamine

    go.drugbank.com/drugs/DB09300
    ApprovedInvestigationalVet approved

    It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. … It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and spasms from occurring.

    Mixtures: BIPASMIN COMPUESTO N, BIPASMIN COMPUESTO NSynonyms: N-butylscopolammonium ion, N-butylscopolammonium
  2. Drug

    Ibandronate

    go.drugbank.com/drugs/DB00710
    ApprovedInvestigational

    [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. … Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to [zoledronic acid], [minodronic acid], and [risedronic acid].

    Mixtures: IBAMIN D3 150 MG/2800 IU FİLM KAPLI TABLET, 3 ADET, İBAMIN D3 150 MG/2800 IU GRANÜL İÇEREN SAŞE ,3 SAŞEProducts: BONVIVA 3MG/3ML ILO IN FER, OSTIVEA 3mg/3ml Solution for IV Injection in Pre-filled Syringe
  3. Drug

    Lanolin

    go.drugbank.com/drugs/DB11112
    Approved

    The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments [L2583]. … Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid [L2580].

    Mixtures: I-defense, Veradex-ECategories: Compounds used in a research, industrial, or household setting
  4. Target

    Potassium voltage-gated channel subfamily E member 1

    go.drugbank.com/bio_entities/BE0000489
    TargetHumans

    Assembly with KCNH2/HERG alpha subunit Kv channel may regulate the rapidly activating component of the delayed rectifying potassium current (IKr) in heart (PubMed:9230439)

    Polypeptides: Potassium voltage-gated channel subfamily E member 1
  5. Target

    C-type lectin domain family 4 member E

    go.drugbank.com/bio_entities/BE0009096
    TargetHumans

    Interacts with signaling adapter Fc receptor gamma chain/FCER1G to form a functional complex in myeloid cells (By similarity).

    Polypeptides: C-type lectin domain family 4 member E
  6. Drug

    Guselkumab

    go.drugbank.com/drugs/DB11834
    ApprovedInvestigational

    IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation [A20357]. … Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23.

    Products: TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/1ML
  7. Drug

    Tranexamic acid

    go.drugbank.com/drugs/DB00302
    ApprovedInvestigational

    Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. … [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986.[L31858]

    Synonyms: trans-4-aminomethylcyclohexane-1-carboxylic acid, trans-4-(Aminomethyl)cyclohexanecarboxylic acidInternational brands: Cyclo-F
  8. Drug

    Vancomycin

    go.drugbank.com/drugs/DB00512
    ApprovedInvestigational

    It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. … Such an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196].

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: VANCOMICINA BONISCONTRO E GAZZONE, Vancomycin Injection USP In 5% Dextrose
  9. Drug

    Ceftriaxone

    go.drugbank.com/drugs/DB01212
    ApprovedInvestigational

    Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. … [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges[A215582], eyes[A215647], and inner ear[A215627].

    Mixtures: CEF-3 INJECTION IM (1G), CEF-3 INJECTION IM (1G)Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-Ring
  10. Drug

    Diazepam

    go.drugbank.com/drugs/DB00829
    ApprovedIllicitInvestigationalVet approved

    It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal … (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the

    Mixtures: Gabavale-5Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates