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Ticlopidine
go.drugbank.com/drugs/DB00208ApprovedIt is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. … The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they
Products: TICLOPIDINA EG, TACRON TABLET 250 mgBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. … It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity.
Mixtures: BISOPROLOLO E IDROCLOROTIAZIDE AUROBINDO, BISOPROLOLO E IDROCLOROTIAZIDE AUROBINDOProducts: BISOPROLOL - CT 5 MG TABL, BISOPROLOL - CT 10 MG TABLNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approvedNotably, if injected into a person not currently using opioid medications, there would be no noticeable effects at all. … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.
Mixtures: TILICOMP BETA 100/8MG RET, TILICOMP BETA 100/8MG RETProducts: NALOKSON HIDROKLORUR ENJ.10AMP(D)(E, NALOXONA 0.4 MG/MLTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigational[L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978.
Mixtures: GANFORT 0.3MG/ML+5MG/ML ED, GANFORT 0.3MG/ML+5MG/ML EDProducts: Blocadren Tab 5mg, Timolol-5 Tab 5mgDarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalThis block reduces the urgency to urinate and so it should not be used in people with urinary retention. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Products: DARUCIL® ER 15 MG, EMSELEX 15MG RETPseudoephedrine
go.drugbank.com/drugs/DB00852ApprovedPseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first ...
Mixtures: GERALGINE-HOT 500 MG+60MG+4MG/11G TEK KULLANIMLIK GRANUL ICEREN POŞET, Medicament Sinus Personnel EX-fort CapletProducts: DEKOFERIN-EX SURUP 150 ML, PSEUDORINE TABLETS 60 mgAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalIt is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia.
Mixtures: Osmolex ER, Osmolex ERProducts: Osmolex ER, AMANTADINA 100 MGNiacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Mixtures: Niacin 500 Mg and Inositol, Ni-C-E-LE PlusProducts: Niaspan ER, Niacin 100 mgLercanidipine
go.drugbank.com/drugs/DB00528ApprovedInvestigationalWithdrawnIt is sold under various commercial names including Zanidip.
Mixtures: LERCAPREL 20 MG/10 MG, ZANIPRESS 10 MG/10 MG FILM TABLET, 30 ADETProducts: LERCANIDIPINA EG, Lercadip 10 mg Filmtabletten