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Phenolphthalein
go.drugbank.com/drugs/DB04824ApprovedWithdrawnPhenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.
Synonyms: 3,3-Bis(4-hydroxyphenyl)phthalideInternational brands: Feen-a-mint gum, Feen-a-mint laxative mintsGliquidone
go.drugbank.com/drugs/DB01251ApprovedThis block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release. … Gliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker.
Categories: Alimentary Tract and Metabolism, Cytochrome P-450 SubstratesProducts: GLURENOR 30 MG TABLETTEN, Glurenorm 30 mg - TablettenDisulfiram
go.drugbank.com/drugs/DB00822ApprovedInvestigationalA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. … When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and
Categories: Scabicides, Insecticides and Repellents, Antiparasitic Products, Insecticides and RepellentsSynonyms: N,N,N',N'-tetraethylthiuram disulfide, 1,1'-dithiobis(N,N-diethylthioformamide)Crotamiton
go.drugbank.com/drugs/DB00265ApprovedCrotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. … It is miscible with alcohol and with methanol.
Categories: Scabicides and Pediculicides, Compounds used in a research, industrial, or household settingProducts: CROTAMITON CREAM 10% v/w, CROTOCORT CREAM 10% W/WAlizapride
go.drugbank.com/drugs/DB01425InvestigationalAlizapride is a dopamine antagonist that is capable of demonstrating both prokinetic and antiemetic effects. … This kind of pharmacological activity makes it effective for use in the treatment of various kinds of nausea and vomiting, including that which may occur postoperatively.
Categories: Heterocyclic Compounds, 1-Ring, Alimentary Tract and MetabolismProducts: ALIZAPRIDA 50 MG/ 2 ML, ALIZAPRIDA SOLUCION INYECTABLE 50 MG/ 2 MLPhenprocoumon
go.drugbank.com/drugs/DB00946ApprovedInvestigationalWithdrawnCoumarin derivative that acts as a long-acting oral anticoagulant.
Synonyms: 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one, 3-(1-Phenylpropyl)-4-hydroxycoumarinCategories: Heterocyclic Compounds, 1-Ring, Blood and Blood Forming OrgansBufexamac
go.drugbank.com/drugs/DB13346ApprovedWithdrawnBufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. … The use of bufexamac has been discontinued in Canada and the United States, which may be due to undetermined clinical efficacy and a high prevalence of contact sensitization [A32822].
Synonyms: 4-Butoxy-N-hydroxybenzeneacetamide, 2-(p-Butoxyphenyl)-acetohydroxamic acidCategories: Non COX-2 selective NSAIDS, Acetic Acid Derivatives and Related SubstancesCorticorelin
go.drugbank.com/drugs/DB05394InvestigationalIt is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. … It is a type of neurohormone, also called hCRF.
Categories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: CRH "Ferring" - Pulver und Lösungsmittel zur Herstellung einer InjektionslösungAcipimox
go.drugbank.com/drugs/DB09055ApprovedInvestigationalAdverse effects include flushing (associated with Prostaglandin D2), palpitations, and GI disturbances. Flushing can be reduced by taking aspirin 20-30 min before taking Acipimox. … Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL.
Categories: Heterocyclic Compounds, 1-Ring, Nicotinic Acid and DerivativesProducts: OLBETAM CAPSULE 250 mgTrolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedIt is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.
Mixtures: ELF Flawless Finish Foundation SPF 15 Oil FreeCategories: Non COX-2 selective NSAIDS