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Displaying results 3821 - 3830 of 10000 in total
  1. Target

    Uridine 5'-monophosphate synthase

    go.drugbank.com/bio_entities/BE0004473
    TargetEnzymeHumans

    -5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP) … Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine

    Polypeptides: Uridine 5'-monophosphate synthase
  2. Target

    5-hydroxytryptamine receptor 1

    go.drugbank.com/bio_entities/BE0004958
    TargetHumans

    Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism (PubMed:18476671, PubMed:20363322, PubMed:20945968). … G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:10452531, PubMed:1565658, PubMed:1652050, PubMed:33762731).

    Polypeptides: 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1BSynonyms: 5-HT1A, 5-HT-1A
  3. Target

    5-hydroxytryptamine receptor 3C

    go.drugbank.com/bio_entities/BE0009584
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3CSynonyms: 5-HT3C, 5-HT3-C
  4. Target

    5-hydroxytryptamine 3 receptor

    go.drugbank.com/bio_entities/BE0009860
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons … Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3BSynonyms: 5-HT-3, 5-HT3A
  5. Target

    5-hydroxytryptamine receptor 3

    go.drugbank.com/bio_entities/BE0010272
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons … Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3BSynonyms: 5-HT-3, 5-HT3A
  6. Drug

    Clobetasol propionate

    go.drugbank.com/drugs/DB01013
    ApprovedInvestigational

    [A190936] Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809] … Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.

    Synonyms: 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate, Clobetasol propionate EInternational brands: Embeline E
  7. Pathway

    Cardiolipin Biosynthesis CL(10:0/10:0/20:0/i-20:0)

    smpdb.ca/view/SMP0175552
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  8. Drug

    Quinine

    go.drugbank.com/drugs/DB00468
    ApprovedInvestigational

    It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. … Quinine (GLS-1200) was also investigated in clinical trials for its efficacy in preventing SARS-CoV-2 infection (NCT04408183, terminated) and is planned to be evaluated for preventing sinusitis after endoscopic

    Synonyms: (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol, (R)-(−)-quinineMixtures: IRUDERM 1
  9. Drug

    Phleum pratense pollen

    go.drugbank.com/drugs/DB10394
    ApprovedInvestigational

    Phleum pratense pollen allergenic extract is used in allergenic testing.

    Mixtures: Oralair 100 IR, ORALAIR 100 IR + 300 IR SublingualtablettenProducts: GRAZAX 75.000 SQ-T ORAL LIYOFILIZAT TABLET, 30 ADET, GRAZAX 75.000 SQ-T ORAL LIYOFILIZAT 100 TABLET
  10. Drug

    Poloxamer 188

    go.drugbank.com/drugs/DB11333
    Approved

    P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217]. … Composed of two hydrophilic side-chains attached to a hydrophobic center core [A27218], its average molecular weight is 8400 Daltons.

    International brands: Lutrol FCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors