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ICX-RHY
go.drugbank.com/drugs/DB05716ExperimentalThe drug was under investigation in clinical trials in the UK for the treatment of skin erosions in recessive dystrophic epidermolysis bulllosa. … ICX-RHY is an investigational therapy comprised of cultured allogeneic fibroblasts.
Dornase alfa
go.drugbank.com/drugs/DB00003ApprovedInvestigationalIn individuals with cystic fibrosis, extracellular DNA, which is an extremely viscous anion, is released by degenerating leukocytes that accumulate during inflammatory responses to infections. … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products without affecting intracellular DNA.
Categories: Enzymes and Coenzymes, Cough and Cold PreparationsBordetella pertussis pertactin antigen
go.drugbank.com/drugs/DB10789ApprovedInvestigationalBordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis [A31248].
Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, Covaxis Injektionssuspension in einer FertigspritzeCategories: Amino Acids, Peptides, and ProteinsDegenerative Joint Disease
go.drugbank.com/conditions/DBCOND0039319Drugs: MethylprednisoloneSynonyms: Osteoarthritis and allied disordersDental Caries Extending Into Dentine
go.drugbank.com/conditions/DBCOND0061100Synonyms: Dental caries confined to enamel and dentineTreosulfan
go.drugbank.com/drugs/DB11678ApprovedInvestigational[L52245] It was approved by the EMA in June 2019[L16965] and by the FDA in January 2025 for use in combination with [fludarabine].[L52575] … Treosulfan is a prodrug alternative to [busulfan] for myeloablative conditioning prior to hematopoietic stem cell transplantation.
Categories: Antineoplastic and Immunomodulating AgentsPimecrolimus
go.drugbank.com/drugs/DB00337ApprovedInvestigationalPimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007. … It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Categories: Skin and Mucous Membrane AgentsCabotegravir
go.drugbank.com/drugs/DB11751ApprovedInvestigational[L31198] While previously administered once monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in … Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, [rilpivirine].
Products: Apretude 30mg Film-Coated Tablet, Apretude 600mg Prolonged-release suspension for injectionTrimethadione
go.drugbank.com/drugs/DB00347ApprovedWithdrawnAn anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
Alveolitis, Extrinsic Allergic
go.drugbank.com/conditions/DBCOND0115831Synonyms: Unspecified allergic alveolitis and pneumonitis