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Displaying results 381 - 390 of 10000 in total
  1. Drug

    Famotidine

    go.drugbank.com/drugs/DB00927
    ApprovedInvestigational

    Famotidine is a competitive histamine-2 (H<sub>2</sub>) receptor antagonist that works to inhibit gastric acid secretion. … It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children.

    Synonyms: N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide, 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidineInternational brands: Sedanium-R
  2. Drug

    Mexiletine

    go.drugbank.com/drugs/DB00379
    ApprovedInvestigational

    Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.

    Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IbSynonyms: 1-(2',6'-dimethylphenoxy)-2-aminopropane, (±)-1-(2,6-dimethylphenoxy)propan-2-amine
  3. Drug

    Lithium carbonate

    go.drugbank.com/drugs/DB14509
    ApprovedInvestigational

    Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label]. … Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843].

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Lithizine Cap 150mg, Lithizine Cap 300mg
  4. Drug

    Sodium iodide

    go.drugbank.com/drugs/DB11119
    ApprovedInvestigational

    Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine. … Radiolabelled compound, [DB09293], is used as a diagnostic tool to evaluate thyroid function and morphology.

    Mixtures: FERTOMCIDINA U, FERTOMCIDINA UProducts: Micro I, ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET
  5. Drug

    Fosinopril

    go.drugbank.com/drugs/DB00492
    ApprovedInvestigational

    Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals … It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Mixtures: FOSINOPRIL E IDROCLOROTIAZIDE AUROBINDO, FOSINOPRIL E IDROCLOROTIAZIDE AUROBINDOCategories: Agents Acting on the Renin-Angiotensin System
  6. Drug

    Orlistat

    go.drugbank.com/drugs/DB01083
    ApprovedInvestigational

    [L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in both over-the-counter[L31963] and prescription preparations, depending on the dosage quantity. … It was approved by the FDA for use in combination with a reduced-calorie diet in 1999.

    Categories: Miscellaneous GI Drugs, Cytochrome P-450 CYP3A InducersProducts: LIPOGRAS® 60 MG CAPSULA CON CONTENIDO LIQUIDO, LIPOGRAS® 120 MG CAPSULA DURA CON CONTENIDO LIQUIDO
  7. Target

    Guanine nucleotide-binding protein G(i) subunit alpha-1

    go.drugbank.com/bio_entities/BE0004491
    TargetHumans

    Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades (PubMed:18434541, PubMed:33762731, PubMed:34239069, PubMed:35610220, PubMed:3793537...

    Polypeptides: Guanine nucleotide-binding protein G(i) subunit alpha-1
  8. Drug

    Ciltacabtagene autoleucel

    go.drugbank.com/drugs/DB16738
    ApprovedInvestigational

    [A245854] Carvykti was first approved by the FDA in February 2022 for the treatment of relapsed or refractory multiple myeloma in treatment-experienced patients.[L40744] … [L40739] Patient T-cells are reprogrammed with a transgene encoding a specific chimeric antigen receptor (CAR) which features two BCMA-targeting single-domain antibodies.

    Synonyms: Autologous bi-epitope BCMA-targeted CAR T-cells
  9. Drug

    Riboflavin

    go.drugbank.com/drugs/DB00140
    ApprovedInvestigationalNutraceuticalVet approved

    It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. … Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast.

    Synonyms: 6,7-Dimethyl-9-D-ribitylisoalloxazine, 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitolMixtures: Super Daily No 2, O-Cal Prenatal Vitamin
  10. Drug

    Fish liver oil

    go.drugbank.com/drugs/DB15481
    ApprovedWithdrawn

    Mixtures: Formula F L W, A+ Zinc TabProducts: Vitamine A 10000 U.I.-cap, Vitamin A Cap 10000unit