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Alfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalIn Canada, it is marketed as ONE-ALPHA, which manages hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in adults with chronic renal failure.
Synonyms: (5Z,7E)-9,10-seco-5,7,10(19)-cholestatrien-1α,3β-diolProducts: ONE-ALPHA 2 MCG/ML IV AMPUL, 10 ADET, ONE-ALPHA 1 MCG/0.5 ML IV AMPUL, 10 ADETMagnesium citrate
go.drugbank.com/drugs/DB11110ApprovedInvestigational[T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg. … [L2831] It is also considered as an active ingredient in over-the-counter products.[L1113]
Mixtures: Q-10 Plus, PCP 100 KitProducts: MAGGZİUM 400 MG ORAL ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 50 ADET, Magnesium 150 mgBaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigational[A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977. … Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients.
Mixtures: Innoprax-5Products: LIORESAL 10 MG TABLET, 50 ADET, COLMIFEN 10 TABLET 10 mgAcetohydroxamic acid
go.drugbank.com/drugs/DB00551ApprovedInvestigationalIn the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
Products: CIPROFLOXACINO 100 MG/10 ML INYECTABLE, CIPROFLOXACINO 100 MG / 10 ML INYECTABLENateglinide
go.drugbank.com/drugs/DB00731ApprovedNateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major metabolites possess less activity than the parent compound. … In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control
Mixtures: NATMET 120/1000 MG TEDAVI PAKETI, 90+90 ADET, NATPLUS 180/1000 MG TEDAVI PAKETI, 90+90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesGlucosamine
go.drugbank.com/drugs/DB01296ApprovedGlucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and findings with unclear clinical significance … [A231894,A232289] It is currently not approved as a prescription product by the FDA, but is widely available over the counter.
Mixtures: GLUCOSAMINE & CHONDROITIN 500/400 MG, FLEXSA PLUS (750 MG/600 MG)Products: FLEXTRIL® 500 MG CAPSULA, VIARTRIL 500 MG CÁPSULASMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Synonyms: (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl esterProducts: MEBENDAZOL 100 MG / 5 ML SUSPENSION, MEBENDAZOL 100 MG/5 ML. SUSPENSIONImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigationalBrian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". … [A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: GLIVEC 100 MG FILM TABLET, 20 ADET, IMAVEC 400 MG KAPSÜL, 30 ADETNimesulide
go.drugbank.com/drugs/DB04743ApprovedWithdrawnDue to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries.
Mixtures: ETNA COMBO 100 MG/8 MG TABLET, 14 ADET, NİMES COMBO 100 MG / 8 MG TABLET , 14 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFormoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigational[A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration … of action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication.
Synonyms: 2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-α-methylphenethyl)amino)ethyl)formanilide, 2'-hydroxy-5'-{1-hydroxy-2-[(p-methoxy-α-methylphenethyl)amino]ethyl}formanilideMixtures: FLUTIFORM® 50 MCG / 5 MCG, FLUTIFORM® 50 MCG / 5 MCG