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Displaying results 381 - 390 of 10000 in total
  1. Drug

    Lithium carbonate

    go.drugbank.com/drugs/DB14509
    ApprovedInvestigational

    Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label]. … Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843].

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: Lithizine Cap 150mg, Lithizine Cap 300mg
  2. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. … The levo-isomer appears to exhibit a very limited antitussive effect.

    Synonyms: d-PropoxypheneMixtures: Novo-propoxyn Compound Cap, Darvocet-N 50
  3. Drug

    Hydroxyethyl Starch

    go.drugbank.com/drugs/DB09106
    ApprovedInvestigational

    HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose. … Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume.

    Mixtures: PF POLIHES (HES 200/0,5) %6 IV INFZÜYON IÇIN ÇÖZELTI, 1000 ML SETSIZ, Hydroxyethyl Starch in Sodium ChlorideCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Riboflavin

    go.drugbank.com/drugs/DB00140
    ApprovedInvestigationalNutraceuticalVet approved

    It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. … Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast.

    Synonyms: 6,7-Dimethyl-9-D-ribitylisoalloxazine, 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitolMixtures: Super Daily No 2, O-Cal Prenatal Vitamin
  5. Target

    Guanine nucleotide-binding protein G(i) subunit alpha-1

    go.drugbank.com/bio_entities/BE0004491
    TargetHumans

    Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades (PubMed:18434541, PubMed:33762731, PubMed:34239069, PubMed:35610220, PubMed:3793537...

    Polypeptides: Guanine nucleotide-binding protein G(i) subunit alpha-1
  6. Drug

    Mexiletine

    go.drugbank.com/drugs/DB00379
    ApprovedInvestigational

    Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.

    Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IbSynonyms: 1-(2',6'-dimethylphenoxy)-2-aminopropane, (±)-1-(2,6-dimethylphenoxy)propan-2-amine
  7. Drug

    Ciltacabtagene autoleucel

    go.drugbank.com/drugs/DB16738
    ApprovedInvestigational

    [A245854] Carvykti was first approved by the FDA in February 2022 for the treatment of relapsed or refractory multiple myeloma in treatment-experienced patients.[L40744] … [L40739] Patient T-cells are reprogrammed with a transgene encoding a specific chimeric antigen receptor (CAR) which features two BCMA-targeting single-domain antibodies.

    Synonyms: Autologous bi-epitope BCMA-targeted CAR T-cells
  8. Drug

    Benzocaine

    go.drugbank.com/drugs/DB01086
    ApprovedInvestigational

    Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. … [A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259]

    Synonyms: p-Carbethoxyaniline, Ethyl p-aminobenzoateMixtures: Oti Cal, FAK Care4 Bus and School Yellow ORM D
  9. Drug

    Cimetidine

    go.drugbank.com/drugs/DB00501
    ApprovedInvestigational

    A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. … It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.

    Synonyms: N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidineMixtures: Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17%, Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40%
  10. Drug

    Fish liver oil

    go.drugbank.com/drugs/DB15481
    ApprovedWithdrawn

    Mixtures: Formula F L W, A+ Zinc TabProducts: Vitamine A 10000 U.I.-cap, Vitamin A Cap 10000unit