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Ivabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigationalTherefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing … Ivabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the
Products: IVABRADIN AL 5MG, IVABRADIN AL 7.5MGDacarbazine
go.drugbank.com/drugs/DB00851ApprovedInvestigationalAn antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564).
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexProducts: AL QUIBAZINA®, TREXTECH® 200 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLENitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approved[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.
Products: AA-Nitrofurantoin Tablet 100mg, Nephronex Tab 50mgAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigationalAcetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N-ACCyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigational[A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond. … [A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury.
Synonyms: (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine, N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamineProducts: Ag-cyclobenzaprine, PMS-cyclobenzaprine - Tab 10mgTravoprost
go.drugbank.com/drugs/DB00287ApprovedInvestigationalTravoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. … [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher efficacy in reducing intraocular pressure and a reduced
Mixtures: TRAVO/TIMOL AL 40UG/ML+5MG, TRAVO/TIMOL AL 40UG/ML+5MGProducts: TRAVOPROST AL 40UG/MLMagnesium
go.drugbank.com/drugs/DB14513ApprovedInvestigationalMagnesium is classified as an alkaline earth metal and has 2 hydration shells. … [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).[A39559]
Mixtures: One A Day Tab, Complete One A Day TabProducts: MAGNEROT A 500 BEUTEL, MAGNESIUM AL 243MG BTACiclopirox
go.drugbank.com/drugs/DB01188ApprovedInvestigationalCiclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.
Products: STIPROX CHAMPU AL 1.5%Leuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigational[A203126, A203132] Leuprolide was first approved in 1985 as a daily subcutaneous injection under the tradename Lupron™ by Abbvie Endocrine Inc. … [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing downstream modulation of both gonadotropin hormone and sex steroid levels.
Products: LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE, LUCRIN DEPOT 1 AY IM/SC 3,75 MG KULLANIMA HAZIR TOZ VE COZUCU ICEREN CIFT BOLMELI ENJEKTORHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigationalHydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine]. … [L8072] It was developed during World War II as a derivative of [quinacrine] with less severe side effects.
Products: Ag-hydroxychloroquine