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Ethoxzolamide
go.drugbank.com/drugs/DB00311ApprovedWithdrawnEthoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confe...
Flucloxacillin
go.drugbank.com/drugs/DB00301ApprovedInvestigationalWithdrawnAntibiotic analog of cloxacillin.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersLevobupivacaine
go.drugbank.com/drugs/DB01002ApprovedInvestigationalWithdrawnLevobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. … general, the majority of potential adverse effects are predominantly associated with inappropriate administration methods that may cause systemic exposure and/or toxicity associated with overexposure to an
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSarracenia Purpurea
go.drugbank.com/drugs/DB13965ApprovedWithdrawnIt was used as an injectable pain reliever and during the 19th century, _Sarracenia purpurea_ was used as a treatment of smallpox [A32509]. … Cytoprotection in an in vitro model of diabetic neuropathy has also been studied. However, the use of Sarracenia Purpurea extracts in the clinical setting are limited.
Products: P-BlocIsothipendyl
go.drugbank.com/drugs/DB08802InvestigationalIsothipendyl is an antihistamine and anticholinergic used as an antipruritic.
Tropicamide
go.drugbank.com/drugs/DB00809ApprovedTropicamide is an alkaloid atropine‐derived anticholinergic drug and a non‐selective antagonist of muscarinic acetylcholine (mACh) receptors.
Mixtures: T-P OFTENO, T-P OFTENOSotalol
go.drugbank.com/drugs/DB00489ApprovedInvestigational[A178579] Sotalol was first approved as an oral tablet on 30 October 1992.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesInternational brands: Tan Shi, Xi An LinSqualene
go.drugbank.com/drugs/DB11460ApprovedInvestigationalVet approvedWithdrawnSqualene is investigated as an adjunctive cancer therapy.
Miocamycin
go.drugbank.com/drugs/DB13287Approvedshown to be effective against several gram-positive and gram-negative microbes and may be useful in the treatment of upper and lower respiratory tract infections, and urogenital tract infections or as an
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsEfalizumab
go.drugbank.com/drugs/DB00095ApprovedWithdrawnIt was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy (PML).[L43797]