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Displaying results 3911 - 3920 of 8700 in total
  1. Drug

    Didesmethylrocaglamide

    go.drugbank.com/drugs/DB15496
    Experimental

    [A186760] While traditionally used for their insecticidal benefits,[A186796] this class of compounds is now being studied for use as chemotherapeutic agents in the treatment of various leukemias, lymphomas

  2. Drug

    Nomegestrol acetate

    go.drugbank.com/drugs/DB13981
    Approved

    Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.

    Categories: Hormonal Contraceptives for Systemic Use, Cytochrome P-450 Substrates
  3. Drug

    Udenafil

    go.drugbank.com/drugs/DB06267
    Approved

    It is not yet approved for use in the U.S., E.U., or Canada.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Pathway

    Disopyramide Cardiac Action Pathway

    smpdb.ca/view/SMP0126247
    Drug action

    Some side effects of using disopyramide may include dizziness, difficulty urinating, dry mouth, and nausea.

    Drugs: Disopyramide · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  5. Pathway

    Mexiletine Action Pathway (New)

    smpdb.ca/view/SMP0126263
    Drug action

    Mexiletine is a class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. Mexiletine (INN) (sold under the brand names Mexitil and Namuscla) is a medication used to treat abnormal h...

    Drugs: Mexiletine · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  6. Pathway

    Procainamide Action Pathway (New)

    smpdb.ca/view/SMP0126265
    Drug action

    The main antidysrythmIc effect is mediated through the sodium channel blockage though. … Some side effects of using procainamide may include cardiac toxicity, bradycardia, hypotension, drug-induced lupus erythematosus-like syndrome, and blood dyscrasias.

    Drugs: Procainamide · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  7. Pathway

    Moricizine Action Pathway

    smpdb.ca/view/SMP0126950
    Drug action

    Moricizine is an antiarrhythmic used to treat arrhythmias (irregular heartbeats) and to maintain normal heart rate. it acts on heart muscles by inhibiting inward sodium channels. This results in a slowed atrioventricular nodal and His-Pu...

    Drugs: Moricizine · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  8. Drug

    Pirepemat

    go.drugbank.com/drugs/DB19165
    Investigational

    Pirepemat is under investigation in clinical trial NCT05258071 (A Clinical Study Evaluating Efficacy of Pirepemat on Falls Frequency in Patients With Parkinson's Disease (PD)).

  9. Drug

    Brepocitinib

    go.drugbank.com/drugs/DB15003
    ApprovedInvestigational

    [L64097] The FDA approved brepocitinib on August 27, 2026 for the treatment of dermatomyositis in adult patients, making it the first targeted oral therapy approved for the condition.[L64115] … Brepocitinib is an oral Janus kinase (JAK) and tyrosine kinase 2 (TYK2) inhibitor used to treat dermatomyositis in adults.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  10. Drug

    Quercus macrocarpa pollen

    go.drugbank.com/drugs/DB10738
    Approved

    Quercus macrocarpa pollen is the pollen of the Quercus macrocarpa plant. Quercus macrocarpa pollen is mainly used in allergenic testing.

    Mixtures: 5-oak Mix, Blackjack/bur/post/red/white PollenSynonyms: bur oak pollen extract