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Pitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigationalMore specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid. … were found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Trolise 4 mg Filmtabletten, ALIPZA 4 MG FILM KAPLI TABLET, 90 ADETMevonlerbart
go.drugbank.com/drugs/DB19416InvestigationalMevonlerbart is under investigation in clinical trial NCT06602726 (A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat Allergy
Synonyms: gamma4 heavy chain Homo sapiens (1-442) [VH (Homo sapiens IGHV3-23*04 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92, Anti-cat allergen fel d 1 monoclonal anitbody regn-1909Peginterferon alfa-2b
go.drugbank.com/drugs/DB00022ApprovedInvestigationalPeginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … When combined together, Peginterferon alfa-2b and [Ribavirin] have been shown to achieve a SVR between 41% for genotype 1 and 75% for genotypes 2-6 after 48 weeks of treatment.
Categories: Compounds used in a research, industrial, or household setting, Hepatitis CSynonyms: PEG-IFN-α-2b, Pegylated Interferon α-2bRWJ-800088
go.drugbank.com/drugs/DB18693InvestigationalRWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous TPO.
Synonyms: -METHOXY-, 1,1'-DIETHER WITH N2,N6-BIS(N-(3-HYDROXY-1-OXOPROPYL)-L-ISOLEUCYL-L-.ALPHA., a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenousDaunorubicin
go.drugbank.com/drugs/DB00694ApprovedInvestigationalA very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione, Leukaemomycin CAbiprubart
go.drugbank.com/drugs/DB19333InvestigationalAbiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395
Synonyms: Gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1, (115-212), hinge 1-12 S10>P (222) (213-224), CH2 LCholestyramine
go.drugbank.com/drugs/DB01432ApprovedInvestigationalCholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. … Cholestyramine resin is quite hydrophilic, but insoluble in water.
Categories: Compounds used in a research, industrial, or household settingProducts: ANTILIP GRANULADO EN SACHET, COLESTIRAMINA 4 G.Calcium
go.drugbank.com/drugs/DB01373ApprovedInvestigationalNutraceuticalBone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. … Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways.
Mixtures: OSSOFORTIN A 70 MG+1200 MG/800 IU TEDAVİ PAKETİ, 4+24 ADET, Calcium With Mg Zn Mn Cu CR Si and Vit. C & DCategories: ascorbic acid (vit C) and calciumErdafitinib
go.drugbank.com/drugs/DB12147ApprovedInvestigationaltool kit to treat such a prevalent medical condition. … [L5956, L5959] Considering urothelial cancer is statistically the fourth most common kind of cancer in the world, the introduction of erdafitinib offers a much-needed new option in the ever-expanding therapeutic
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: BALVERSA 4 MG FİLM KAPLI TABLET, 28 ADET, BALVERSA 4 MG FİLM KAPLI TABLET, 56 ADETAcylcarnitine 11-{3,4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoylcarnitine
smpdb.ca/view/SMP0123496MetabolicOnce inside the cell it undergoes a reaction to form an acyl-CoA derivative called 11-{3,4-dimethyl-5-[(1E)-prop-1-en-1-yl]furan-2-yl}undecanoyl-CoA. … This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety to appropriate acyl groups.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more