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Displaying results 3961 - 3970 of 5895 in total
  1. Drug

    RO-7293583

    go.drugbank.com/drugs/DB17455
    Investigational

    RO-7293583 is a TYRP1-Targeting CD3 T-Cell Engager.

  2. Drug

    Phosphoaminophosphonic acid guanylate ester

    go.drugbank.com/drugs/DB02082
    Experimental

    A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+.

  3. Drug

    Zebularine

    go.drugbank.com/drugs/DB03068
    Experimental

    Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. … It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates.

    Synonyms: Pyrimidin-2-one ribonucleoside, pyrimidin-2-one beta-ribofuranoside
  4. Drug

    Cyclopropane

    go.drugbank.com/drugs/DB13984
    Experimental

    Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene. … Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive.

  5. Drug

    Tovecimig

    go.drugbank.com/drugs/DB30220
    Investigational

    NOV1501 is under investigation in clinical trial NCT03292783 (This is a Study to Evaluate the Safety and Tolerability of the Study Drug ABL001, and to Determine the Maximum Tolerated Dose and/or Recommended

  6. Drug

    Palifosfamide

    go.drugbank.com/drugs/DB05668
    Investigational

    Ifosfamide has been shown to be effective in high doses in treating testicular cancer, sarcoma and lymphoma.

  7. Drug

    Perifosine

    go.drugbank.com/drugs/DB06641
    Investigational

    Perifosine is a novel alkylphospholipid with antiproliferative properties attributed to protein kinase B inhibition.

  8. Drug

    1-benzylimidazole

    go.drugbank.com/drugs/DB04581
    Experimental

    1-benzylimidazole, an N-imidazole derivative, has been shown to have strong cardiotonic activity.

  9. Drug

    ARCT-810

    go.drugbank.com/drugs/DB17683
    Investigational

    ARCT-810 is an mRNA replacement therapy that delivers ornithine transcarbamylase mRNA to hepatocytes.

  10. Drug

    EB05

    go.drugbank.com/drugs/DB16477
    Investigational

    EB05, in combination with standard of care (SOC), is being investigated in clinical trial NCT04401475 to evaluate its safety and efficacy in adult hospitalized patients with COVID-19 and ARDS.