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Displaying results 3971 - 3980 of 10000 in total
  1. Drug

    Atecegatran metoxil

    go.drugbank.com/drugs/DB12507
    Investigational

    Atecegatran metoxil has been used in trials studying the basic science and prevention of Nonvalvular Atrial Fibrillation, Persistent or Permanent Nonvalvular Atrial Fibrillation, and Persistent or Permanent

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    PS386113

    go.drugbank.com/drugs/DB05211
    Experimental

    Little information has been released about PS386113. … PS386113 is a small molecule drug candidate under investigation for the treatment of inflammatory disorders. It is being developed by Schering-Plough and Pharmacopeia.

  3. Drug

    AMG-222

    go.drugbank.com/drugs/DB06011
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Medical Cannabis

    go.drugbank.com/drugs/DB14009
    Investigational

    The use of the plant species _Cannabis sativa_ and _Cannabis indica_, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical conditions as a … In contrast to THC's weak agonist activity, CBD has been shown to act as a negative allosteric modulator of the cannabinoid CB1 receptor, the most abundant G-Protein Coupled Receptor (GPCR) in the body

    Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein inhibitors
  5. Drug

    Mersalyl

    go.drugbank.com/drugs/DB09338
    Experimental

    Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. … Interestingly, it has been found to have antiviral properties in mice [L1584].

  6. Target

    Nuclear cap-binding protein subunit 2

    go.drugbank.com/bio_entities/BE0013483
    TargetHumans

    (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene

    Synonyms: Cell proliferation-inducing gene 55 protein
  7. Drug

    ASP-3026

    go.drugbank.com/drugs/DB12729
    Investigational

    ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies, Positive for Anaplastic Lymphoma Kinase, and Positive for Proto-Oncogene Tyrosine-Protein

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Rociletinib

    go.drugbank.com/drugs/DB11907
    Investigational

    Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.

    Categories: Heterocyclic Compounds, 1-Ring, Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
  9. Drug

    6-O-benzylguanine

    go.drugbank.com/drugs/DB11919
    Investigational

    6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: O(6)-Benzylguanine
  10. Drug

    HMR4011

    go.drugbank.com/drugs/DB06225
    Experimental

    IPL 576,092 has previously been investigated as a treatment for asthma. … HMR4011 (IPL 576,092) is a novel steroidal anti-inflammatory compound with a mechanism of action distinct from that of glucocorticoid.