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Displaying results 3971 - 3980 of 10000 in total
  1. Target

    Interleukin-5 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0003471
    TargetHumans

    Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed:1495999, PubMed:22528658).

    Polypeptides: Interleukin-5 receptor subunit alphaSynonyms: IL-5 receptor subunit alpha
  2. Target

    5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

    go.drugbank.com/bio_entities/BE0003891
    TargetVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

    Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. … Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose

    Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: 5'-deoxyadenosine nucleosidase, 5'-methylthioadenosine nucleosidase
  3. Target

    Proteasome subunit alpha type-5

    go.drugbank.com/bio_entities/BE0003914
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...

    Polypeptides: Proteasome subunit alpha type-5Synonyms: alpha-5, Proteasome subunit alpha-5
  4. Target

    5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

    go.drugbank.com/bio_entities/BE0004031
    TargetEscherichia coli O157:H7

    Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. … Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose

    Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: 5'-deoxyadenosine nucleosidase, 5'-methylthioadenosine nucleosidase
  5. Target

    Keratin-associated protein 5-2

    go.drugbank.com/bio_entities/BE0004492
    TargetHumans

    In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through ...

    Polypeptides: Keratin-associated protein 5-2Synonyms: Keratin-associated protein 5-8
  6. Target

    5'(3')-deoxyribonucleotidase, cytosolic type

    go.drugbank.com/bio_entities/BE0004774
    EnzymeHumans

    Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP (Ref.12).

    Polypeptides: 5'(3')-deoxyribonucleotidase, cytosolic typeSynonyms: Deoxy-5'-nucleotidase 1, Cytosolic 5',3'-pyrimidine nucleotidase
  7. Target

    5'-AMP-activated protein kinase

    go.drugbank.com/bio_entities/BE0004907
    TargetTransporterHumans

    Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357, PubMed:24563466, PubMed:31492851, PubMed:37821951...

    Polypeptides: 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit beta-2
  8. Target

    Keratin, type II cytoskeletal 5

    go.drugbank.com/bio_entities/BE0009087
    TargetHumans

    Structural component of intermediate filaments in basal keratinocytes of stratified epithelia. Forms heteropolymers with type I partners including KRT14 and KRT15, contributing to the formation of the keratin intermediate filament networ...

    Polypeptides: Keratin, type II cytoskeletal 5Synonyms: CK-5, Keratin-5
  9. Target

    Protein arginine N-methyltransferase 5

    go.drugbank.com/bio_entities/BE0011121
    TargetHumans

    Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA (PubMed:10531356, PubMed:11152681, PubMed:11747828, P...

    Polypeptides: Protein arginine N-methyltransferase 5
  10. Target

    Inositol polyphosphate 5-phosphatase OCRL

    go.drugbank.com/bio_entities/BE0013933
    EnzymeHumans

    Also, is able to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate (PubMed:15474001, PubMed:40969890, PubMed:7761412). … Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic

    Polypeptides: Inositol polyphosphate 5-phosphatase OCRLSynonyms: Inositol polyphosphate 5-phosphatase OCRL-1, Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase