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Displaying results 31 - 34 of 34 in total
  1. Pathway

    Ethanol Degradation

    smpdb.ca/view/SMP0000449
    Metabolic

    The acetate leaves the mitochondria and moves to extra-hepatic tissues for further metabolism. … Ethanol degradation occurs via four pathways, three of which are oxidative pathways and are depicted here.

    Drugs: Adenosine phosphate · NADH · ATP · Ethanol · Zinc · Mesoheme +2 more
  2. Pathway

    Disulfiram Aldehyde Dehydrogenase Inhibitor Action Pathway

    smpdb.ca/view/SMP0122693
    Drug action

    The compound also affects fatty acid transporters that are responsible for transferring reducing equivalents and oxidization as they are sensitive to acetaldehyde. … Acetaldehyde that accumulates in the mitochondrial matrix inhibits energy production seen by its inhibition of respiratory control and oxidative phosphorylation as some examples.

    Drugs: Adenosine phosphate · NADH · ATP · Disulfiram · Ethanol · Zinc +3 more
  3. Pathway

    Ethanol Glycine Agonist Action Pathway

    smpdb.ca/view/SMP0126452
    Drug action

    This causes an influx of chlorine ions which hyperpolarizes the neuron. Glycine receptors are present mainly in the spinal cord and brain stem where they control motor function. … The main effects are seen by the binding to GABA receptors, glycine receptors, and glutamate receptors. Ethanol agonizes glycine receptors, where glycine binds to the alpha subunit.

    Drugs: Glycine · Ethanol · Calcium
  4. Pathway

    Ethanol NMDA Antagonist Action Pathway

    smpdb.ca/view/SMP0126453
    Drug action

    In preventing their depolarization, ethanol prevents the creation and storage of memories. … This prevents the calcium channel from opening and allowing calcium into to the post-synaptic neuron.

    Drugs: L-Glutamine · Glutamic acid · Ethanol · Calcium