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Glyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigationalGlyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin se...
Mixtures: DUO-ANGLUCID, GLIBOMETCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesFingolimod
go.drugbank.com/drugs/DB08868ApprovedInvestigationalMultiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relap...
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: FINGOLIMOD DR. REDDY'SPerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalPerindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration....
Products: PERINDOPRIL ERB 1A PH 4MGHydrochlorothiazide
go.drugbank.com/drugs/DB00999ApprovedInvestigationalVet approvedHydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension. Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combinati...
Mixtures: LOSARTAN-KAL HCTAD100/25, LOSARTAN KAL HCTAD 100/25Products: DI-ERTRIDE TABLET 25 mg, Nu-hydroMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[A180799,A180805] Previously, mycophenolic acid (MPA) was administered to individuals with autoimmune diseases beginning in the 1970s, but was discontinued due to gastrointestinal effects and concerns … It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.[A180826]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: MICOFENOLATO MOFETILE DR. REDDY'S, Van-mycophenolateVitamin E
go.drugbank.com/drugs/DB00163ApprovedInvestigationalNutraceuticalVet approvedIn 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. … Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage[A176104].
Mixtures: VITAMIN D3 1.25 MG 50000 IU Dietary Supplement, Virt-PnCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersRosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigational[A181084] Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD. … [A181090,A181093,A181096,A181427,A181475,A181538] Statins are considered a cost-effective treatment option for CVD due to their evidence of reducing all-cause mortality including fatal and non-fatal CVD
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: ROVARIL® 10 MG CAPSULAS BLANDAS DE GELATINA, ROSUVASTATIN HEC PH 5MGBupropion
go.drugbank.com/drugs/DB01156ApprovedInvestigationalbrand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an … [A6399,A178810] Bupropion was originally classified as an "atypical" antidepressant because it does not exert the same effects as the classical antidepressants such as Monoamine Oxidase Inhibitors (
Mixtures: Appbutamone-DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesHydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedDue to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [ … Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing
Products: Dr Lucid Hydrogen Peroxide 4%, Dr. Lift Hydrogen Peroxide 3 PercentAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received...
Mixtures: PLENACOR DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates