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Displaying results 391 - 400 of 10000 in total
  1. Drug

    Epinastine

    go.drugbank.com/drugs/DB00751
    Approved

    It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding … to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic

    Synonyms: 3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepineInternational brands: Kai lai Zhi
  2. Drug

    Modified Cholera toxin A subunit

    go.drugbank.com/drugs/DB18556
    Experimental

    Synonyms: Modified Cholera toxin A subunit
  3. Drug

    Virginiamycin M1

    go.drugbank.com/drugs/DB01669
    Experimental

    Pristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and one component of pristinamycin. It is produced by Streptomyces graminofaciens and other bacteria.

    Categories: Streptogramin Group ASynonyms: Mikamycin A, Ostreogrycin A
  4. Drug

    Desoxyribonuclease

    go.drugbank.com/drugs/DB09551
    ApprovedInvestigational

    Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. … The enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration of the ion is independent of the enzyme concentration [A31251].

    Synonyms: Deoxyribonuclease A, Deoxyribonuclease I bovineMixtures: FIBRASE SA
  5. Drug

    Dapiprazole

    go.drugbank.com/drugs/DB00298
    Approved

    Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.

    Synonyms: 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridineCategories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor Antagonists
  6. Drug

    Tideglusib

    go.drugbank.com/drugs/DB12129
    ApprovedInvestigationalWithdrawn

    It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). … [A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012.

    Synonyms: 4-BENZYL-2-(A-NAPHTYL)-1,2,4-THIADIAZOLIDINE-3,5-DIONE, 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dioneCategories: Heterocyclic Compounds, 1-Ring, Glycogen Synthase Kinase 3, antagonists & inhibitors
  7. Drug

    Rotavirus vaccine

    go.drugbank.com/drugs/DB10276
    ApprovedInvestigational

    Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains.[L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain.

    Salts: Human Rotavirus A type G1P(8) strain RIX4414 live antigen, Human Rotavirus A type G1P7(5) strain WI79 live antigenMixtures: ROTATEQ® VACUNA ORAL PENTAVALENTE CONTRAROTAVIRUS, ROTATEQ® VACUNA ORAL PENTAVALENTE CONTRAROTAVIRUS
  8. Drug

    Galidesivir

    go.drugbank.com/drugs/DB11676
    Investigational

    [L12042] Because of its activity against other coronaviruses, it may be studied as a potential therapy for COVID-19. … Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus.

    Synonyms: Immucillin A, Immucillin-ACategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    Trazodone

    go.drugbank.com/drugs/DB00656
    ApprovedInvestigational

    [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms, or insomnia, which are commonly associated with SSRI and SNRI therapy. … [T646] Trazodone acts on various receptors, including certain histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a narrow range of neurotransmitters

    Synonyms: 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneCategories: P-glycoprotein inducers, Cytochrome P-450 Substrates
  10. Drug

    Ammonio methacrylate copolymer type A

    go.drugbank.com/drugs/DB12031
    Investigational

    Ammonio methacrylate copolymer type a has been used in trials studying the treatment of GERD.

    Synonyms: Ammonio methacrylate copolymer type AInternational brands: Eudragit RL 30 D