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Rolicyclidine
go.drugbank.com/drugs/DB01549ExperimentalIllicitBecause of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in the USA in the 1970s.
Nitroarginine
go.drugbank.com/drugs/DB04223InvestigationalAn inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. … Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)
Lanifibranor
go.drugbank.com/drugs/DB14801InvestigationalLanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337).
DYN-101
go.drugbank.com/drugs/DB17921InvestigationalDYN-101 is an antisense product candidate designed to reduce the expression of dynamin 2 protein.
Veverimer
go.drugbank.com/drugs/DB18977InvestigationalVeverimer is under investigation in clinical trial NCT03390842 (Long-term Safety Extension to Study TRCA-301).
Clorindione
go.drugbank.com/drugs/DB13275ExperimentalClorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans.
NRP290
go.drugbank.com/drugs/DB06383ExperimentalNRP290 is a hydrocodone derivative under investigation for the treatment of pain (moderate to moderately severe).
Alcuronium
go.drugbank.com/drugs/DB13648ExperimentalA non-depolarizing skeletal muscle relaxant similar to [tubocurarine]. It is used as an anesthesia adjuvant.
Propionate ion
go.drugbank.com/drugs/DB19384InvestigationalPropionate ion is under investigation in clinical trial NCT00846326 (Preventing Tolerance to Oxymetazoline in Allergic Rhinitis).
Orgotein
go.drugbank.com/drugs/DB11444ExperimentalVet approvedThe antioxidant mechanism of SOD is common to most organisms exposed to oxygen. A notable exception is Lactobacillus plantarum. … Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage.