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Displaying results 4021 - 4030 of 10000 in total
  1. Drug

    PF-05175157

    go.drugbank.com/drugs/DB12096
    Investigational

    PF-05175157 has been used in trials studying the basic science and treatment of Acne Vulgaris, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus Type 2, and Diabetes Mellitus, Type 2, among

  2. Drug

    Onercept

    go.drugbank.com/drugs/DB06495
    Investigational

    Synonyms: R-HTBP-1
  3. Drug

    OSI-461

    go.drugbank.com/drugs/DB05415
    Investigational

    OSI-461 is a second-generation molecule belonging to a new class of drugs termed selective apoptotic anti-neoplastic drugs (SAANDs).

  4. Drug

    AVR-RD-04

    go.drugbank.com/drugs/DB18644
    Experimental

    AVR-RD-04 is an investigational gene therapy for cystinosis. … It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.

    Synonyms: autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin
  5. Drug

    Cry5B

    go.drugbank.com/drugs/DB17783
    Experimental

    Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis_. … With demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal infections.[A259372, A259377]

  6. Drug

    Bicuculline

    go.drugbank.com/drugs/DB11562
    Experimental

    Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. … It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.

    Synonyms: d-BicucullineCategories: GABA-A Receptor Antagonists, Heterocyclic Compounds, 2-Ring
  7. Drug

    Ultevursen

    go.drugbank.com/drugs/DB17835
    Investigational

    Ultevursen is a single-stranded RNA-based oligonucleotide targeting exon 13 of the USH2A gene that encodes usherin.

  8. Target

    Tyrosine-protein kinase ABL2

    go.drugbank.com/bio_entities/BE0000435
    TargetHumans

    and adhesion and receptor endocytosis. … Phosphorylates multiple receptor tyrosine kinases like PDGFRB and other substrates which are involved in endocytosis regulation such as RIN1.

    Synonyms: Abelson-related gene protein
  9. Drug

    Vasomera

    go.drugbank.com/drugs/DB16498
    Investigational

    Categories: Receptors, G-Protein-Coupled
  10. Drug

    Daleuton

    go.drugbank.com/drugs/DB00154
    InvestigationalNutraceutical

    A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.

    Synonyms: (Z,Z,Z)-8,11,14-Icosatrienoate, (Z,Z,Z)-8,11,14-Eicosatrienoic acid