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Displaying results 4031 - 4040 of 7063 in total
  1. Drug

    Icalcaprant

    go.drugbank.com/drugs/DB21651
    Investigational

    Icalcaprant has a monoisotopic molecular weight of 406.2 Da. … Icalcaprant is a small molecule drug. The usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist.

  2. Drug

    Olomorasib

    go.drugbank.com/drugs/DB21697
    Investigational

    Olomorasib has a monoisotopic molecular weight of 528.08 Da. … Olomorasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.

  3. Drug

    Istisociclib

    go.drugbank.com/drugs/DB21703
    Investigational

    Istisociclib has a monoisotopic molecular weight of 287.21 Da. … Istisociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Istisociclib is a cyclin dependant kinase inhibitor.

  4. Drug

    Atirmociclib

    go.drugbank.com/drugs/DB21733
    Investigational

    Atirmociclib has a monoisotopic molecular weight of 463.18 Da. … Atirmociclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Atirmociclib is a cyclin dependant kinase inhibitor.

  5. Drug

    Itopride

    go.drugbank.com/drugs/DB04924
    Investigational

    Itopride is a dopamine D2 antagonist with acetylcholinesterase inhibitory actions.

  6. Drug

    CA-074 methyl ester

    go.drugbank.com/drugs/DB07223
    Experimental

    CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]

    Synonyms: CA 074 Me ester, CA 074 methyl ester
  7. Drug

    Vilanterol

    go.drugbank.com/drugs/DB09082
    ApprovedInvestigational

    Vilanterol is a selective long-acting β2-adrenergic agonist (LABA) with inherent 24-hour activity for the once-daily treatment of COPD and asthma. … [A259961] Vilanterol is 1000 and 400 fold more selective for β2 than β1 and β3 adrenoceptors, respectively, with a faster onset of action than salmeterol.

  8. Drug

    Carbazochrome

    go.drugbank.com/drugs/DB09012
    ApprovedWithdrawn

    either at a local or systemic level [A19744]. … It is not FDA-approved but is available as tablets or IM/SC injections in the treatment of hemorrhages in a number of countries.

    International brands: Di Ka Ning, Ge Dan
  9. Drug

    Nylidrin

    go.drugbank.com/drugs/DB06152
    ApprovedWithdrawn

    Nylidrin is a peripheral vasodilator. … Therefore, the FDA has withdrawn nylidrin from the U.S. market [L2286].

  10. Drug

    Berotralstat

    go.drugbank.com/drugs/DB15982
    ApprovedInvestigational

    Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). … [L26661] Berotralstat was approved by the European Commission on April 30, 2021 [L41965] and by Health Canada on June 06, 2022.