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Displaying results 4051 - 4060 of 8700 in total
  1. Drug

    Abciximab

    go.drugbank.com/drugs/DB00054
    ApprovedWithdrawn

    It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells. … Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules

    Categories: Glycoprotein IIb/IIIa Receptor-directed Monoclonal Antibodies
  2. Drug

    Aluminum oxide

    go.drugbank.com/drugs/DB11342
    ApprovedWithdrawn

    It is considered an indirect additive used in food contact substances by the FDA.

    Categories: Anti-Acne Preparations for Topical Use
  3. Target

    Kainate receptors

    go.drugbank.com/bio_entities/BE0009793
    TargetHumans

    L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. … L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system (By similarity).

    Polypeptides: Glutamate receptor ionotropic, kainate 1, Glutamate receptor ionotropic, kainate 2Synonyms: Glutamate receptor 5, Glutamate receptor 6
  4. Drug

    Prezatide

    go.drugbank.com/drugs/DB11296
    Approved

    Prezatide is used in cosmetic products for the skin and hair.

  5. Drug

    Siagoside

    go.drugbank.com/drugs/DB12351
    Investigational

    Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. Sygen appears to be beneficial in patients with severe spinal cord injury. … Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease.

  6. Drug

    Trovafloxacin

    go.drugbank.com/drugs/DB00685
    ApprovedWithdrawn

    Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the a...

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  7. Drug

    Serabelisib

    go.drugbank.com/drugs/DB14935
    Investigational

    Serabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics

  8. Drug

    Capreomycin

    go.drugbank.com/drugs/DB00314
    ApprovedInvestigational

    Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.

    Categories: Antiinfectives for Systemic Use, Drugs for Treatment of Tuberculosis
  9. Drug

    Allogeneic Cardiosphere-Derived Cells

    go.drugbank.com/drugs/DB15744
    Investigational

    They exert their effects by secreting exosomes: nanometer-sized, membrane-bound vesicles used for the purpose of cell-cell communication.

  10. Drug

    Veru-111

    go.drugbank.com/drugs/DB16462
    Investigational

    VERU-111, an investigational drug intended for various therapeutic uses, was under investigation in clinical trials NCT04842747, NCT03752099, NCT04388826, NCT04844749, NCT05008510, and NCT05079360.

    Categories: Experimental Unapproved Treatments for COVID-19