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Displaying results 4051 - 4060 of 10000 in total
  1. Drug

    3,3'-diindolylmethane

    go.drugbank.com/drugs/DB11875
    Investigational

    Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-Ring
  2. Drug

    Dexanabinol

    go.drugbank.com/drugs/DB06444
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Metixene

    go.drugbank.com/drugs/DB00340
    Approved

    Metixene (or methixene) is a anticholinergic used as an antiparkinsonian agent.

    Categories: Heterocyclic Compounds, 3-Ring, Serotonin 5-HT2 Receptor Antagonists
  4. Drug

    Desirudin

    go.drugbank.com/drugs/DB11095
    ApprovedWithdrawn

    It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. … Desirudin is a direct inhibitor of human thrombin.

  5. Drug

    Diiodohydroxyquinoline

    go.drugbank.com/drugs/DB09115
    Approved

    Diiodohydroxyquinoline, also known as uidoquinol and iodoquinol, is a quinoline derivative that can be used in the treatment of amoebiasis. The exact mechanism of action is unknown. … Iodoquinol is not currently available in any FDA-approved products.

    Mixtures: Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1%, Alcortin ACategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Mitotane

    go.drugbank.com/drugs/DB00648
    ApprovedInvestigational

    It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is used off-label for the management of Cushing's syndrome.[A263016] … Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InducersSynonyms: 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene, o,p'-DDD
  7. Drug

    Avacincaptad pegol

    go.drugbank.com/drugs/DB15165
    ApprovedInvestigational

    [L47696] AMD is the leading cause of vision loss in developed countries for people over 50 years old, with a global estimate of 170 million individuals affected. … This approval is based on the positive results obtained from 2 phase 3 clinical trials GATHER1 and GATHER2.[L47701]

  8. Drug

    Etorphine

    go.drugbank.com/drugs/DB01497
    ExperimentalIllicitVet approved

    In certain countries, etorphine is classified as a Schedule 1 drug and hence, in these countries, it can be used legally only by health professionals and for research purposes. … A narcotic analgesic morphinan used as a sedative in veterinary practice.

    Categories: Heterocyclic Compounds with 4 or More Rings
  9. Drug

    Tarenflurbil

    go.drugbank.com/drugs/DB05289
    Investigational

    It is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. … Tarenflurbil is an investigational drug that was studied in patients with mild Alzheimer's disease.

    Synonyms: (R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acid, (−)-(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid
  10. Drug

    Sulodexide

    go.drugbank.com/drugs/DB06271
    ApprovedInvestigationalWithdrawn

    Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).

    Products: VESSEL DUE F, VESSEL DUE F 250 LSU CAPSULE