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Amdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnAmidinopenicillanic acid derivative with broad spectrum antibacterial action. It is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseBeractant
go.drugbank.com/drugs/DB06761ApprovedBeractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. … In comparison to synthetic forms of surfacant, natural forms such as Beractant have been found to have a reduced incidence of pneumothorax and reduced mortality.
Vemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigational[A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF. … [A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann La Roche.
Sinecatechins
go.drugbank.com/drugs/DB01266ApprovedInvestigationalNutraceuticalSinecatechins is a botanical drug product for topical use. … Catechins constitute 85 to 95% (by weight) of the total drug substance which includes more than 55% of Epigallocatechin gallate (EGCg), other catechin derivatives such as Epicatechin (EC), Epigallocatechin
Motexafin lutetium
go.drugbank.com/drugs/DB05296InvestigationalMotexafin lutetium (MLu) is a second-generation photosensitizer for photodynamic therapy (PDT) of cancer. It belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin.
Categories: Heterocyclic Compounds with 4 or More RingsAcenocoumarol
go.drugbank.com/drugs/DB01418ApprovedInvestigationalCoumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation.
Lifileucel
go.drugbank.com/drugs/DB17107ApprovedInvestigational] Lifileucel was granted accelerated approval by the FDA on February 16, 2024, for the treatment of unresectable or metastatic melanoma. … Lifileucel is a tumour-derived autologous T cell immunotherapy composed of a suspension of tumour-derived T cells from the patient [L50171] which undergo isolation, ex vivo expansion, and activation[A263341
Ezatiostat
go.drugbank.com/drugs/DB05460InvestigationalThese are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen … Ezatiostat is investigated in clinical trials for treating myelodysplastic syndrome. This compound belongs to the peptides.
Paquinimod
go.drugbank.com/drugs/DB13118InvestigationalPaquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease. … Current treatments of SLE are NSAID (nonsteroidal anti-inflammatory drugs), corticosteroids, antimalarians or cytotoxic drugs like for example Cyclophosphamide.