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Mesoridazine
go.drugbank.com/drugs/DB00933ApprovedWithdrawnA phenothiazine antipsychotic with effects similar to chlorpromazine.
Products: Serentil Tab 25mg, Serentil Tab 10mgNifedipine
go.drugbank.com/drugs/DB01115ApprovedInvestigational[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. … [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer durations of action.
Mixtures: Seaford Nifedipine and Lidocaine Hydrochloride CreamCategories: atenolol and nifedipine, nifedipine and diureticsThiopental
go.drugbank.com/drugs/DB00599ApprovedInvestigationalVet approvedWithdrawnIt does not produce any excitation but has poor analgesic and muscle relaxant properties. Small doses have been shown to be anti-analgesic and lower the pain threshold. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p920)
Categories: Hypnotics and SedativesProducts: PENTOTEX INJECTION 0.5G (10ML), Pentothal Inj 25mg/mlMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.
Mixtures: IMPLICOR 25MG/5MG FILM-COATED TABLETS, IMPLICOR 50MG/5MG FILM-COATED TABLETSCategories: metoprolol and thiazides, metoprolol and felodipineIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States.
Categories: Skin and Mucous Membrane AgentsProducts: ISODERM 20MG, ISOGALEN 20MGAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigationalAzathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic … [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesProducts: AZATHIOPRIN AL 25MG FTA, AZATHIOPRIN AQVIDA 25MGDidanosine
go.drugbank.com/drugs/DB00900ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative
Categories: Nucleic Acids, Nucleotides, and Nucleosides, Nucleoside and Nucleotide Reverse Transcriptase InhibitorsProducts: Videx Chewable Dispersible Tab 25mg, Videx Chewable Dispersible Tab 100mgOxtriphylline
go.drugbank.com/drugs/DB01303ApprovedIt is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available. … Oxtriphylline is the choline salt form of [theophylline].
Categories: Xanthines and Adrenergics, choline theophyllinate and adrenergicsProducts: Rouphylline Syr 10mg/ml, PMS Oxtriphylline Syr Pediatric 10mg/mlBromelains
go.drugbank.com/drugs/DB13281ApprovedInvestigationalBromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase … It works by selectively inhibiting the biosynthesis of proinflammatory prostaglandins [A27197] and also has analgesic properties, as well as anticancerous and pro-apoptotic effects.
Mixtures: Bromelain and Papain Tab, Pancreatin and Enzyme Formula - TabletCategories: Enzymes and Coenzymes, Preparations for Treatment of Wounds and UlcersErtugliflozin
go.drugbank.com/drugs/DB11827ApprovedInvestigationalIt works to block glucose reabsorption from the glomerulus.[A31581] Ertugliflozin was first approved by the FDA in December 2017. … [A261951, L1132] It was also approved by the European Commission in March 2018.[L48621]
Mixtures: Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets, Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated TabletsCategories: Alimentary Tract and Metabolism, metformin and ertugliflozin