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Displaying results 401 - 410 of 10000 in total
  1. Drug

    Octreotide

    go.drugbank.com/drugs/DB00104
    ApprovedInvestigational

    On June 26, 2020, the first approved delayed-release oral somatostatin analog, Mycapssa, received FDA approval for the long term maintenance treatment of acromegaly. … [L14513] Additionally, it is used for the treatment of acromegaly and symptoms arising from various tumors, including carcinoid tumors and vasoactive intestinal tumors (VIPomas).

    Products: SANDOSTATIN LAR FOR INJECTION 10 mg, SANDOSTATIN LAR FOR INJECTION 20 mg
  2. Indication

    No prior therapy for metastatic disease

    go.drugbank.com/conditions/DBCOND0130369
    Drugs: Hyaluronidase (human recombinant) · Nivolumab · Pertuzumab · Sacituzumab govitecan · Trastuzumab
    Synonyms: No prior therapy for metastatic disease
  3. Drug

    Methylprednisolone

    go.drugbank.com/drugs/DB00959
    ApprovedInvestigationalVet approved

    [A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. … Methylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone].[A188811] It was first described in the literature in the late 1950s.

    Mixtures: Methylprednisolone Sodium Succinate for Injection, USP, Methylprednisolone Sodium Succinate for Injection, USPCategories: Compounds used in a research, industrial, or household setting, Corticosteroids for Systemic Use
  4. Drug

    Artemisia frigida pollen

    go.drugbank.com/drugs/DB10493
    Approved

    Artemisia frigida pollen is the pollen of the Artemisia frigida plant. Artemisia frigida pollen is mainly used in allergenic testing.

    Mixtures: Number Four Weed Mixture, Sage Mix, Common/dark-leaved/dragon/pasture PollenCategories: Non-Standardized Pollen Allergenic Extract
  5. Drug

    Hyaluronidase

    go.drugbank.com/drugs/DB14740
    ApprovedInvestigational

    [A199026] Hyaluronidase has been used in surgical settings for at least the past 60 years to improve the diffusion of local anesthetics. … [A199047] Hyaluronidase was first used in prescription products in the United States on 5 May 2004.[L13338]

    Products: HYALASE POWDER FOR INJECTION 1500 iu/ampoule, Wydase Inj 150unit/ml
  6. Drug

    DL-alpha tocopheryl acetate

    go.drugbank.com/drugs/DB14477
    Approved

    Mixtures: Fizz Multivitamins for Kids W C Loz, Megavite RxProducts: Vitamin E 200iu With Non-med.odorless Garlic, EGOGYN 1000 UI
  7. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections. … [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat

    Mixtures: METARSAL N CAPSULAS, DIARSET NX® M CAPSULASCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Benzocaine

    go.drugbank.com/drugs/DB01086
    ApprovedInvestigational

    [A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259] … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.

    Mixtures: BUCOSEPTOL N, CVS Health Healing on the Go KitCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Anesthetics for Topical Use
  9. Pathway

    The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria

    smpdb.ca/view/SMP0002359
    Disease

    This results in modulations of HIF-mediated hypoxia responses and alterations in gene expression through global epigenetic remodelling that may contribute to malignant transformation. 2-Hydroxyglutarate … A mutation in IDH causes high concentrations of D-2-Hydroxyglutaric acid. D-2-hydroxyglutarate is a competitive inhibitor of 2OG-dependent dioxygenases resulting in genetic changes and malignancies.

    Drugs: Pyruvic acid · Biotin · L-Glutamine · Succinic acid · Glutamic acid · NADH +6 more
  10. Drug

    Fludarabine

    go.drugbank.com/drugs/DB01073
    ApprovedInvestigational

    Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.

    Products: Fludarabine Kabi 50mg Lyophilized Powder for Solution for Injection or Infusion, Fludarabine Sandoz 50 mg/2ml concentrate for solution for injection or infusion