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Displaying results 401 - 410 of 10000 in total
  1. Drug

    Papaverine

    go.drugbank.com/drugs/DB01113
    ApprovedInvestigational

    The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels. … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation.

    Categories: Heterocyclic Compounds, 2-Ring, Drugs Used in Erectile DysfunctionProducts: PAPAVERİN HCL GALEN 50 MG/2 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL, PAPAVERIN HCL BIOFARMA 50 MG / 2ML AMPUL, 100 ADET
  2. Drug

    Ambroxol

    go.drugbank.com/drugs/DB06742
    ApprovedInvestigational

    Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. … It stimulates synthesis and release of surfactant by type II pneumocytes.

    Synonyms: Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)-, N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanolMixtures: AMBROXOL 15 MG+ CLENBUTEROL 10 MCG /5 ML, AMBROXOL 150 MG / 100 ML + CLENBUTEROL 0.1 MG / 100 ML SOLUCIÓN ORAL NIÑOS
  3. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. … [L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]

    Mixtures: ARTENSOL® H 40 MG TABLETAS, Inderide-40 TabCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT1A Receptor Antagonists
  4. Drug

    Menadione

    go.drugbank.com/drugs/DB00170
    ApprovedNutraceutical

    A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

    Mixtures: LIBAVIT-K 20 MG AMPUL, 5 ADETCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP1A2 Inhibitors
  5. Drug

    Octreotide

    go.drugbank.com/drugs/DB00104
    ApprovedInvestigational

    [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. … On June 26, 2020, the first approved delayed-release oral somatostatin analog, Mycapssa, received FDA approval for the long term maintenance treatment of acromegaly.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: SANDOSTATIN LAR 10 MG, SANDOSTATIN LAR 20 MG.
  6. Drug

    Nizatidine

    go.drugbank.com/drugs/DB00585
    Approved

    A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.

    Synonyms: N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamineProducts: AXID 25 MG/ML IV IMF. ICIN ENJ. AMPUL, 5 ADET, AXID INYECTABLE 100 MG/4 ML
  7. Drug

    Amphotericin B

    go.drugbank.com/drugs/DB00681
    ApprovedInvestigational

    mcg/mL in vitro. … Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0

    Categories: Compounds used in a research, industrial, or household settingProducts: ABELCET 100 MG/20 ML IV INF. ICIN. SUS. ICEREN FLAKON, 1 ADET, AMPHOLIP ®50 MG/10 ML
  8. Drug

    Butylscopolamine

    go.drugbank.com/drugs/DB09300
    ApprovedInvestigationalVet approved

    It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. … It is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms.

    Synonyms: N-butylscopolammonium, N-butylscopolammonium ionMixtures: MOLIT PLUS 500 MG / 10 MG TABLET, 20 ADET, TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 20 ADET
  9. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    Diphenhydramine is also used in combination with [DB14132] as the anti-nausea drug [DB00985] where it is utilized primarily for its antagonism of H1 histamine receptors within the vestibular system [A1540 … However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352].

    Synonyms: 2-(benzhydryloxy)-N,N-dimethylethylamine, 2-diphenylmethoxy-N,N-demthylethanamineInternational brands: Dormarex 2
  10. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    It is a water-soluble analogue of [camptothecin], which is extracted from the Chinese tree _Camptotheca acuminate_. … [A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl