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Displaying results 4111 - 4120 of 10000 in total
  1. Target

    UDP-glucose 6-dehydrogenase

    go.drugbank.com/bio_entities/BE0000645
    TargetHumans

    Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans (PubMed:21502315, PubMed:21961565, PubMed:22123821, PubMed:23106432, PubMed:25478983, PubMed:27966912, PubMed:30420606, PubMed:30457329). Req...

    Polypeptides: UDP-glucose 6-dehydrogenase
  2. Target

    Maltose-6'-phosphate glucosidase

    go.drugbank.com/bio_entities/BE0001309
    TargetBacillus subtilis (strain 168)

    Hydrolyzes maltose-6'-phosphate and trehalose-6'-phosphate. … Is also able to significantly catalyze the hydrolysis of both 6-phospho-alpha- and 6-phospho-beta-glucosides containing activated leaving groups such as p-nitrophenol and does so with retention and inversion

    Polypeptides: Maltose-6'-phosphate glucosidaseSynonyms: 6-phospho-alpha-D-glucosidase, 6-phosphoryl-O-alpha-D-glucopyranosyl:phosphoglucohydrolase
  3. Target

    6-phospho-beta-galactosidase

    go.drugbank.com/bio_entities/BE0001435
    TargetLactococcus lactis subsp. lactis

    Polypeptides: 6-phospho-beta-galactosidaseFunction: 6-phospho-beta-galactosidase activity
  4. Target

    6-deoxyerythronolide B hydroxylase

    go.drugbank.com/bio_entities/BE0001638
    TargetSaccharopolyspora erythraea (strain NRRL 23338)

    Catalyzes the conversion of 6-deoxyerythronolide B (6-DEB) to erythronolide B (EB) by the insertion of an oxygen at the 6S position of 6-DEB.

    Polypeptides: 6-deoxyerythronolide B hydroxylaseSynonyms: 6-DEB hydroxylase
  5. Target

    UDP-glucose 6-dehydrogenase

    go.drugbank.com/bio_entities/BE0002000
    TargetStreptococcus pyogenes

    Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis.

    Polypeptides: UDP-glucose 6-dehydrogenase
  6. Drug

    Exametazime

    go.drugbank.com/drugs/DB11179
    Approved

    It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. … Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection.

    Products: BRAIN-SPECT RADYOFARMASÖTIK HAZIRLAMA KITI, 6 FLAKON, CERETEC FOR INJECTION 0.5 mg/vial
  7. Drug

    Paricalcitol

    go.drugbank.com/drugs/DB00910
    ApprovedInvestigational

    Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels.

    Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesProducts: PARACALCITOLO SUN, ZEMPLAR 4 MCG YUMUŞAK KAPSÜL, 28 ADET
  8. Drug

    Anbenitamab

    go.drugbank.com/drugs/DB18411
    Investigational

    Synonyms: FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific IgG1 antibody inhibiting PD-L1 and CTLA-4, IMMUNOGLOBULIN G1 (369-SERINE,371-ALANINE,408-LYSINE,410-VALINE), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR HER2 DOMAIN IV)(HUMAN-MUS MUSCULUS MONOCLONAL RHUMAB 4D5 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS
  9. Drug

    Oxcarbazepine

    go.drugbank.com/drugs/DB00776
    ApprovedInvestigational

    [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood … - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the name [eslicarbazepine].

    Categories: P-glycoprotein inducers, P-glycoprotein substratesSynonyms: 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
  10. Target

    5-hydroxytryptamine receptor 6

    go.drugbank.com/bio_entities/BE0000945
    TargetHumans

    G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:35714614, PubMed:36989299, PubMed:37327704, PubMed:8522988). Also has a high affinit...

    Polypeptides: 5-hydroxytryptamine receptor 6Synonyms: 5-HT-6, Serotonin receptor 6