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Diethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawn(Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.[L43942]
Categories: Hormonal Contraceptives for Systemic Use, P-glycoprotein substratesPF-05175157
go.drugbank.com/drugs/DB12096InvestigationalPF-05175157 has been used in trials studying the basic science and treatment of Acne Vulgaris, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus Type 2, and Diabetes Mellitus, Type 2, among
Dexamethasone isonicotinate
go.drugbank.com/drugs/DB11487ExperimentalVet approvedIts unintended mineralocorticoid action may cause salt and water retention. … Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 SubstratesDG041
go.drugbank.com/drugs/DB05027ExperimentalDG041, an anti-platelet compound, has shown to be a selective and potent antagonist of the EP3 receptor for prostaglandins E2. … DG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and its complications.
Desvenlafaxine
go.drugbank.com/drugs/DB06700ApprovedInvestigational[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD). … Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.
Categories: Antidepressive Agents Indicated for Depression, Cytochrome P-450 SubstratesCOVID-19 convalescent plasma
go.drugbank.com/drugs/DB15692Investigational), and use for single patients through an emergency IND (eIND; 21 CFR 312.310). … [L14333] This investigational COVID-19 treatment is currently available through three main pathways: use in registered clinical trials, use through the expanded access COVID-19 protocol (21 CFR 312.305
Categories: Experimental Unapproved Treatments for COVID-19scyllo-inositol
go.drugbank.com/drugs/DB03106InvestigationalAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. … Scyllitol has been investigated for the treatment of Alzheimer Disease.
Delafloxacin
go.drugbank.com/drugs/DB11943ApprovedInvestigationalIt was approved in June 2017 under the trade name Baxdela for use in the treatment of acute bacterial skin and skin structure infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseAlmitrine
go.drugbank.com/drugs/DB01430ApprovedAlmitrine is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies.
Synonyms: 2,4-Bis(allylamino)-6-(4-(bis(p-fluorophenyl)methyl)-1-piperazinyl)-s-triazineCrofelemer
go.drugbank.com/drugs/DB04941ApprovedInvestigationalIt is marketed under the brand name Fulyzaq and indicated for the symptomatic treatment of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy.