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Displaying results 4121 - 4130 of 10000 in total
  1. Drug

    Latrunculin A

    go.drugbank.com/drugs/DB02621
    Investigational

    Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer.

    Synonyms: (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one, LAT-A
  2. Drug

    Esuberaprost

    go.drugbank.com/drugs/DB18464
    Investigational

    Esuberaprost (GP-1681), a drug intended for participants with pulmonary arterial hypertension, was under investigation in clinical trial NCT03657095 to evaluate its efficacy and safety.

    Synonyms: (+)-4-((1r,2r,3as,8bs)-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4-methyl-oct-1-en-6-yn-1-yl)-2,3,3a,8b-tetrahydro-1h-cyclopenta(b)(1)benzofuran-5-yl)butanoic acid, 1h-cyclopenta(b)benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4-methyl-1-octen-6-ynyl)-, (1r,2r,3as,8bs)-
  3. Drug

    Estradiol valerate

    go.drugbank.com/drugs/DB13956
    ApprovedInvestigationalVet approved

    [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%). … The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle.

    Mixtures: DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET, DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADETCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  4. Drug

    Ketoconazole

    go.drugbank.com/drugs/DB01026
    ApprovedInvestigational

    Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. … [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole] and [clotrimazole], due to its broad spectrum and good absorption.

    Mixtures: CLINDAMICINA/KETOCONAZOL 100 MG/400MG, Ketoconazole 2% / Salicylic Acid 2%Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  5. Drug

    Ensovibep

    go.drugbank.com/drugs/DB19078
    Investigational

    Ensovibep is under investigation in clinical trial NCT04501978 (ACTIV-3: Therapeutics for Inpatients With COVID-19).

    Synonyms: Designed ankyrin repeat protein (synthetic bivalent human albumin-binding) fusion protein with designed ankyrin repeat protein (synthetic trivalent severe acute respiratory syndrome coronavirus 2 spike
  6. Drug

    Dimethylaminomicheliolide

    go.drugbank.com/drugs/DB17111
    Investigational

    Synonyms: AZULENO(4,5-B)FURAN-2(3H)-ONE, 3-((DIMETHYLAMINO)METHYL)-3A,4,5,7,8,9,9A,9B-OCTAHYDRO-9-HYDROXY-6,9-DIMETHYL-, (3R,3AS,9R,9AS,9BS)-Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Dexchlorpheniramine maleate

    go.drugbank.com/drugs/DB09555
    Approved

    Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. … Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.

    Mixtures: HUFADEXTA-M, Rescon MXCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
  8. Drug

    Calmangafodipir

    go.drugbank.com/drugs/DB18398
    Investigational

    Synonyms: Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine) manganese complexes trisodium trihydrogen manganate, Calmangafodipir (ca4mn(dpdp)5)Categories: Vitamin B Complex, Heterocyclic Compounds, 1-Ring
  9. Drug

    Fluorofuranylnorprogesterone F-18

    go.drugbank.com/drugs/DB15282
    Investigational

    Fluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).

    Synonyms: 19-NORPREGN-4-ENE-3,20-DIONE, 21-(FLUORO-18F)-16,17-((R)-(2-FURANYLMETHYLENE)BIS(OXY))-, (16.ALPHA.)-, FFNP F-18
  10. Drug

    Pheniramine

    go.drugbank.com/drugs/DB01620
    Approved

    Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine].

    Mixtures: ANTIBEKSIN SURUP, 100 ML, Opcon-ACategories: Heterocyclic Compounds, 1-Ring