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Displaying results 4181 - 4190 of 10000 in total
  1. Drug

    Dexpanthenol

    go.drugbank.com/drugs/DB09357
    ApprovedInvestigational

    Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. … Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that are important for protein metabolism

    Mixtures: NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET, nasic - Nasenspray für Kinder 5 mg/500 mgCategories: Vitamin B Complex, Vitamin D and Analogues
  2. Drug

    Anvatabart opadotin

    go.drugbank.com/drugs/DB18290
    Investigational

    Synonyms: Immunoglobulin G1-kappa, anti-[Homo sapiens ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody, F (pAF) (121), K120 (217) (121- 218), hinge 1-15 (219
  3. Drug

    Englumafusp alfa

    go.drugbank.com/drugs/DB19341
    Investigational

    and in Combination With Glofitamab Following a Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/refractory B-cell Non-hodgkin's Lymphoma). … Englumafusp alfa is under investigation in clinical trial NCT04077723 (A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab

    Synonyms: 71-248-4-1BB ligand (human precursor) fusion protein with peptide linker (GGGGS)2 fusion protein with 71-248-4-1BB ligand (human precursor) peptide linker (GGGGS)2 fusion protein with human κ-chain C region, 4- 1BB ligand (tumor necrosis factor ligand superfa
  4. Drug

    Haloperidol

    go.drugbank.com/drugs/DB00502
    ApprovedInvestigational

    (mainly D2), particularly within the mesolimbic and mesocortical systems of the brain. … Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide.

    Synonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-oneInternational brands: Einalon S
  5. Drug

    DPDPE

    go.drugbank.com/drugs/DB08861
    Experimental

    A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.

    Synonyms: L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-D-valine, cyclic (2-5)-disulfide, (D-Pen2,D-Pen5)-Enkephalin
  6. Drug

    Gentamicin

    go.drugbank.com/drugs/DB00798
    ApprovedInvestigationalVet approved

    Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity

    Mixtures: GENTAMICINA 0.1% + DEXAMETASONA 0.04% + KETOCONAZOL 2% CREMA, INDOBIOTIC GOZ DAMLASI, 5 MLCategories: OCT2 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  7. Drug

    Loperamide

    go.drugbank.com/drugs/DB00836
    ApprovedInvestigational

    [A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.

    Mixtures: Dg Health Anti Diarrheal Anti GasCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  8. Drug

    Uttroside B

    go.drugbank.com/drugs/DB18633
    Experimental

    Synonyms: -d-galactopyranoside, (3.beta.,5.alpha.,22.alpha.,25r)-26-(.beta.-d-glucopyranosyloxy)-22-hydroxyfurostan-3-yl o-.beta.-d-glucopyranosyl-(1->2)-o-(.beta.-d-xylopyranosyl-(1->3))-o-.beta., -d-glucopyranosyl-(1->4)-
  9. Drug

    Fenvalerate

    go.drugbank.com/drugs/DB18391
    Experimental

    Synonyms: -cyano-3-phenoxybenzyl (2rs)-2-(4-chlorophenyl)-3-methylbutyrate, -cyano-3-phenoxybenzyl (rs)-2-(4-chloro-phenyl)-3-methylbutyrateCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP3A Inhibitors
  10. Drug

    Dexamethasone

    go.drugbank.com/drugs/DB01234
    ApprovedInvestigationalVet approved

    Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms

    Mixtures: NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/MLCategories: P-glycoprotein inducers, P-glycoprotein inhibitors