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Suzetrigine
go.drugbank.com/drugs/DB18927ApprovedInvestigationalblocker with analgesic properties[A264948] Na<sub>V</sub>1.8 is abundantly expressed in peripheral sensory nerves to play a role in pain signal transmission, making it a desirable therapeutic target for
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP2B6 InducersSulfaisodimidine
go.drugbank.com/drugs/DB13283ExperimentalSulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has been … officially approved for use anywhere [A175672].
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UsePertussis vaccine
go.drugbank.com/drugs/DB15274ApprovedInvestigationalPertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
Mixtures: Infanrix-IPV+Hib Pulver und Suspension zur Herstellung einer InjektionssuspensionNeisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen
go.drugbank.com/drugs/DB10799ApprovedInvestigationalNeisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria
Neisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen
go.drugbank.com/drugs/DB10800ApprovedInvestigationalNeisseria meningitidis group y capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria
Acebutolol Action Pathway
smpdb.ca/view/SMP0000296Drug actionAdrenaline (also known as epinephrine) can activate β1 adrenergic receptor so that the heart rate and output will be increased. … Acebutolol (also known as Sectral or Prent) is a selective β1 adrenergic receptor antagonist (beta blocker), which can be used for treatment of high blood pressure (hypertension) and irregular heartbeats
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Penbutolol Action Pathway
smpdb.ca/view/SMP0000305Drug actionPenbutolol (also known as Levatol or Levatolol) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Penbutolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the b...
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Lidocaine (Antiarrhythmic) Action Pathway
smpdb.ca/view/SMP0000328Drug actionThis pathway illustrates the lidocaine targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cells m...
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Mexiletine Action Pathway
smpdb.ca/view/SMP0000329Drug actionMexiletine may be used to treat ventricular arrhythmias.
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Carvedilol Action Pathway
smpdb.ca/view/SMP0000367Drug actionThis effect may prevent free radical damage to treat chronic heart failure.
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2