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3-oxo-5-alpha-steroid 4-dehydrogenase 2
go.drugbank.com/bio_entities/BE0000585TargetEnzymeHumansCatalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed … Converts testosterone into 5-alpha-dihydrotestosterone (DHT), the most active androgen in the prostate, as it is the preferred ligand for androgen receptor (AR) transactivation, making this reaction a
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 2Synonyms: 5 alpha-SR2, Type II 5-alpha reductaseA disintegrin and metalloproteinase with thrombospondin motifs 5
go.drugbank.com/bio_entities/BE0003730TargetHumansMetalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chon...
Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 5Synonyms: ADAMTS-5, ADAM-TS 5Actin-related protein 2/3 complex subunit 5
go.drugbank.com/bio_entities/BE0004255TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in th...
Polypeptides: Actin-related protein 2/3 complex subunit 5Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
go.drugbank.com/bio_entities/BE0009517TargetHumansPreferentially utilizes GTP, rather than ATP, for PI(5)P phosphorylation and its activity reflects changes in direct proportion to the physiological GTP concentration (PubMed:26774281).
Polypeptides: Phosphatidylinositol 5-phosphate 4-kinase type-2 betaSynonyms: PI(5)P 4-kinase type II beta, PtdIns(5)P-4-kinase isoform 2-betaPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma
go.drugbank.com/bio_entities/BE0009518TargetHumansPhosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity.
Polypeptides: Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaSynonyms: PI(5)P 4-kinase type II gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gammacAMP-specific 3',5'-cyclic phosphodiesterase 4 (PDE4)
go.drugbank.com/bio_entities/BE0009963TargetHumansHydrolyzes the second messenger 3',5'-cyclic AMP (cAMP), which is a key regulator of many important physiological processes
Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4A, 3',5'-cyclic-AMP phosphodiesterase 4BFunction: 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-AMP phosphodiesterase activityPefloxacin
go.drugbank.com/drugs/DB00487ApprovedA synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingProducts: PEMAX TABLET 400 mgBifonazole
go.drugbank.com/drugs/DB04794ApprovedBifonazole is an azole antifungal drug.
Mixtures: CANESTEN ULTRA UÑAS 1%Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2E1 InhibitorsElosulfase alfa
go.drugbank.com/drugs/DB09051ApprovedInvestigationalThe recommended dose is 2 mg per kg given intravenously over a minimum range of 3.5 to 4.5 hours, based on infusion volume, once every week. … Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome.
Synonyms: Recombinant human N-acetylgalactosamine-6-sulfatase, Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS)Products: VIMIZIM® 1MG/ML SOLUCIÓN CONCENTRADA PARA INFUSIÓN, Vimizim 1mg/ml Concentrate for Solution for InfusionCalcium Phosphate
go.drugbank.com/drugs/DB11348ApprovedInvestigationalCalcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Mixtures: MULTIVIT M® CAPSULAS, Multivitamines Et MinerauxCategories: ascorbic acid (vit C) and calcium, Compounds used in a research, industrial, or household setting