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Displaying results 411 - 420 of 10000 in total
  1. Drug

    Ertugliflozin

    go.drugbank.com/drugs/DB11827
    ApprovedInvestigational

    It works to block glucose reabsorption from the glomerulus.[A31581] Ertugliflozin was first approved by the FDA in December 2017. … [A261951, L1132] It was also approved by the European Commission in March 2018.[L48621]

    Mixtures: Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets, Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated TabletsCategories: Alimentary Tract and Metabolism, metformin and ertugliflozin
  2. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Categories: Skin and Mucous Membrane AgentsProducts: Up and Up Minoxidil, Up and Up minoxidil
  3. Drug

    Sodium fluoride

    go.drugbank.com/drugs/DB09325
    ApprovedInvestigational

    and is highly effective in reducing the prevalence of caries. … Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18].

    Mixtures: Up and Up Sensitive Toothpaste, Up and Up Sensitive Toothpaste WhiteningCategories: Mouthwashes and Gargles, Alimentary Tract and Metabolism
  4. Drug

    Vortioxetine

    go.drugbank.com/drugs/DB09068
    ApprovedInvestigational

    Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional … agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors.

    Products: KELAC® 10MG, Brintellix 20mg Film-coated Tablets
  5. Drug

    Hydroxyzine

    go.drugbank.com/drugs/DB00557
    ApprovedInvestigational

    [A189753] Hydroxyzine is also used for generalized anxiety disorder, tension caused by psychoneurosis, and other conditions with manifestations of anxiety.[L9677] … Hydroxyzine is a first-generation histamine H<sub>1</sub>-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.

    Categories: Miscellaneous Anxiolytics Sedatives and HypnoticsProducts: Atarax Cap 25mg, Multipax Cap 25mg
  6. Drug

    Lanolin

    go.drugbank.com/drugs/DB11112
    Approved

    Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. … The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments [L2583].

    Mixtures: Baby Bum, Up and Up Diaper RashCategories: Basic Ointments and Protectants
  7. Drug

    Tapentadol

    go.drugbank.com/drugs/DB06204
    ApprovedInvestigational

    [A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.

    Products: PALEXIS® RETARD 25MG, NUCYNTA ER Tablets 250mg
  8. Pathway

    Glutaminolysis and Cancer

    smpdb.ca/view/SMP0002298
    Disease

    Glutamine not only provides a major substrate for respiration but also for the synthesis of other macromolecules, such as nucleotides, proteins and hexosamines. … The transportation of glutamine in and out regulates mTOR activation to coordinate cell growth and proliferation.

    Drugs: Pyridoxal phosphate · Pyruvic acid · Biotin · Aspartic acid · L-Glutamine · Succinic acid +9 more
  9. Drug

    Methyl salicylate

    go.drugbank.com/drugs/DB09543
    ApprovedInvestigationalVet approved

    The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. … Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens.

    Mixtures: Up and Up Pain, Up and Up Pain Relief Ultra StrengthProducts: US Favorite Hot Pain Relieving, Neuro Max Pain and Muscle Relief Gel
  10. Drug

    Conjugated estrogens

    go.drugbank.com/drugs/DB00286
    ApprovedInvestigational

    Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble. … The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material.

    Mixtures: Esterified Estrogens and Methyltestosterone, Esterified Estrogens and MethyltestosteroneCategories: Genito Urinary System and Sex Hormones, conjugated estrogens and bazedoxifene