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Displaying results 4211 - 4220 of 10000 in total
  1. Target

    3-oxo-5-alpha-steroid 4-dehydrogenase

    go.drugbank.com/bio_entities/BE0004887
    EnzymeTargetHumans

    Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT) (PubMed:17986282, PubMed:26855069) … Catalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed

    Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 1, 3-oxo-5-alpha-steroid 4-dehydrogenase 2Synonyms: 5 alpha-SR2, Steroid 5-alpha-reductase 1
  2. Target

    Very long chain fatty acid elongase 5

    go.drugbank.com/bio_entities/BE0009375
    EnzymeTargetHumans

    Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- a...

    Polypeptides: Very long chain fatty acid elongase 5Synonyms: ELOVL FA elongase 5, ELOVL fatty acid elongase 5
  3. Target

    Mitogen-activated protein kinase kinase kinase 5

    go.drugbank.com/bio_entities/BE0018876
    TargetHumans

    Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determ...

    Polypeptides: Mitogen-activated protein kinase kinase kinase 5Synonyms: MEKK 5, MEK kinase 5
  4. Target

    T cell receptor beta variable 5-6

    go.drugbank.com/bio_entities/BE0023691
    TargetHumans

    V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and ...

    Polypeptides: T cell receptor beta variable 5-6
  5. Drug

    Cerebrolysin

    go.drugbank.com/drugs/DB16599
    Investigational

    Products: Ambotonin 215,2 mg/ml - parenterale Lösung Injektionslösung/Konzentrat zur Herstellung einer Infusionslösung
  6. Drug

    Treosulfan

    go.drugbank.com/drugs/DB11678
    ApprovedInvestigational

    Treosulfan is a prodrug alternative to [busulfan] for myeloablative conditioning prior to hematopoietic stem cell transplantation. … [L52245] It was approved by the EMA in June 2019[L16965] and by the FDA in January 2025 for use in combination with [fludarabine].[L52575]

    Synonyms: L-threitol-1,4-dimethanesulfonateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  7. Drug

    Amithiozone

    go.drugbank.com/drugs/DB12829
    Investigational

    Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection.

    Products: CITAZON 150 MG TABLET, 50 ADET, CİTAZON 150 MG TABLET, 500 ADET
  8. Drug

    Pirenoxine

    go.drugbank.com/drugs/DB15945
    Investigational

    Categories: Heterocyclic Compounds, 1-RingProducts: KARY UNI OPHTHALMIC SUSPENSION 0.05 mg/ml
  9. Drug

    Clostridium tetani toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10583
    ApprovedInvestigational

    It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. … Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection.

    Mixtures: TETADİF 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON, 10 AMPUL, TETADİF 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON, 50 AMPULProducts: TETAVAX 0.5 ML IM/SC ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, T-VAC 0,5 ML IM ENJEKSIYON IÇIN SÜSPANSIYON IÇEREN AMPUL
  10. Drug

    Bufexamac

    go.drugbank.com/drugs/DB13346
    ApprovedWithdrawn

    It has also been used in suppositories in combination with local anaesthetics indicated for haemorrhoids. … Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac.

    Synonyms: 2-(p-Butoxyphenyl)-acetohydroxamic acid, 4-Butoxy-N-hydroxybenzeneacetamideCategories: Non COX-2 selective NSAIDS